P10632 | CP2C8_HUMAN | Cytochrome P450 2C8 (CYP2C8)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00067 | p450 - Cytochrome P450 | 30~487 |
3D structures mapped by conservation among orthologs
[ Domain: "Cytochrome P450" // p450 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3925961 |  |
IC50 | = | 300.0 | nM | 537.63 | CNC(C)C(=O)Nc1ccc(-c2c(-c3ccncc3)nc3cc(C)ccn23)c(C#Cc2ccc3ncccc3c2)n1 | Homo sapiens | CHEMBL3889225 | tissue-based format |
| CHEMBL3969750 |  |
IC50 | = | 300.0 | nM | 553.63 | CNC(C)C(=O)Nc1ccc(-c2c(-c3ccncc3)nc3cc(C)ccn23)c(C#Cc2ccc(-c3ccon3)cc2)n1 | Homo sapiens | CHEMBL3889225 | tissue-based format |
| CHEMBL3910478 |  |
IC50 | = | 500.0 | nM | 551.65 | CNC(C)C(=O)Nc1ccc(-c2c(-c3ccncc3)nc3cc(C)ccn23)c(C#Cc2ccc3nc(C)ccc3c2)n1 | Homo sapiens | CHEMBL3889225 | tissue-based format |
| CHEMBL3911035 |  |
IC50 | = | 900.0 | nM | 565.68 | CN[C@@H](C)C(=O)Nc1ccc(-c2c(-c3ccnc(C)c3)nc3cc(C)ccn23)c(C#Cc2ccc3c(C)nccc3c2)n1 | Homo sapiens | CHEMBL3889225 | tissue-based format |