P10586 | PTPRF_HUMAN | Receptor-type tyrosine-protein phosphatase F (PTPRF)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
Accession | Domain | Range | Color |
---|---|---|---|
PF00041 | fn3 | 321–405 | |
PF00041 | fn3 | 415–505 | |
PF00041 | fn3 | 514–598 | |
PF00041 | fn3 | 609–699 | |
PF00041 | fn3 | 711–811 | |
PF00041 | fn3 | 832–904 | |
PF00041 | fn3 | 919–1005 | |
PF00102 | Y_phosphatase | 1375–1606 | |
PF00102 | Y_phosphatase | 1664–1897 | |
PF07679 | I-set | 33–124 | |
PF07679 | I-set | 136–216 | |
PF07679 | I-set | 232–315 |
3D structures mapped by conservation among orthologs
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // fn3 ]
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // I-set ]
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // I-set_2 ]
[ Domain: "(Phosphotyrosine protein) phosphatases II" // Y_phosphatase ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
---|---|---|---|---|---|---|---|---|---|---|
CHEMBL564699 | IC50 | = | 380.0 | nM | 409.57 | CC1(C)SCC(CCCCC(=O)Nc2ccc3c(c2)C[C@@H](C(=O)O)OC3)S1 | Homo sapiens | CHEMBL1054000 | single protein format | |
CHEMBL556636 | IC50 | = | 382.3 | nM | 409.57 | CC1(C)SCC(CCCCC(=O)Nc2ccc3c(c2)CO[C@H](C(=O)O)C3)S1 | Homo sapiens | CHEMBL1054000 | single protein format | |
CHEMBL549372 | IC50 | = | 458.3 | nM | 381.52 | CC1(C)SCC(CCC(=O)Nc2ccc3c(c2)CO[C@H](C(=O)O)C3)S1 | Homo sapiens | CHEMBL1054000 | single protein format | |
CHEMBL556076 | IC50 | = | 493.0 | nM | 381.52 | CC1(C)SCC(CCC(=O)Nc2ccc3c(c2)C[C@@H](C(=O)O)OC3)S1 | Homo sapiens | CHEMBL1054000 | single protein format | |
CHEMBL550662 | IC50 | = | 624.7 | nM | 345.42 | O=C(CCCc1cccs1)Nc1ccc2c(c1)CO[C@H](C(=O)O)C2 | Homo sapiens | CHEMBL1054000 | single protein format | |
CHEMBL200117 | IC50 | = | 690.0 | nM | 569.74 | CCCCCCCCCCCCCCc1ccc(C(=O)c2ccc3c(-c4ccc(OCC(=O)O)cc4)nocc2-3)cc1 | Homo sapiens | CHEMBL865883 | single protein format | |
CHEMBL570779 | IC50 | = | 765.3 | nM | 345.42 | O=C(CCCc1cccs1)Nc1ccc2c(c1)C[C@@H](C(=O)O)OC2 | Homo sapiens | CHEMBL1054000 | single protein format |