P10144 | GRAB_HUMAN | Granzyme B (GZMB)
Pfam Domain Table
Accession | Domain | Range | Color |
---|---|---|---|
PF00089 | Trypsin - Trypsin | 21~240 |
3D structures mapped by conservation among orthologs
[ Domain: "FMN-binding split barrel 2" // Trypsin_1 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
---|---|---|---|---|---|---|---|---|---|---|
CHEMBL304368 | Ki | = | 8.0 | nM | 500.55 | CC[C@H](C)[C@@H](C(=O)N[C@H]1CCc2cccc3c2N(C1=O)[C@H](C(=O)N[C@H](C=O)C(=O)O)C3)N(C)C(C)=O | Homo sapiens | CHEMBL684582 | single protein format | |
CHEMBL428244 | Ki | = | 8.0 | nM | 500.55 | CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@H]1CCc2cccc3c2N(C1=O)[C@H](C(=O)N[C@H](C=O)CC(=O)O)C3 | Homo sapiens | CHEMBL948945 | single protein format | |
CHEMBL71493 | Ki | = | 13.0 | nM | 556.67 | CC[C@H](C)[C@H](NC(=O)Cc1ccccc1)C(=O)N[C@H]1CCc2cccc3c2N(C1=O)[C@H](C(=O)NCc1cn[nH]c1)C3 | Homo sapiens | CHEMBL684582 | single protein format | |
CHEMBL305293 | Ki | = | 13.0 | nM | 474.51 | CC[C@H](C)[C@H](NC(C)=O)C(=O)NCC(=O)N1c2ccccc2C[C@H]1C(=O)N[C@H](C=O)CC(=O)O | Homo sapiens | CHEMBL684582 | single protein format | |
CHEMBL303031 | Ki | = | 16.0 | nM | 572.62 | CC[C@H](C)[C@@H](C(=O)N[C@H]1CCc2cccc3c2N(C1=O)[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)C(=O)OC)C3)N(C)C(C)=O | Homo sapiens | CHEMBL684582 | single protein format | |
CHEMBL306381 | Ki | = | 38.0 | nM | 495.58 | CC[C@H](C)[C@@H](C(=O)N[C@H]1CCc2cccc3c2N(C1=O)[C@H](C(=O)NCc1cn[nH]n1)C3)N(C)C(C)=O | Homo sapiens | CHEMBL684582 | single protein format | |
CHEMBL303944 | Ki | = | 74.0 | nM | 496.57 | CC[C@H](C)[C@@H](C(=O)N[C@H]1CCc2cccc3c2N(C1=O)[C@H](C(=O)NCc1nn[nH]n1)C3)N(C)C(C)=O | Homo sapiens | CHEMBL684582 | single protein format | |
CHEMBL304727 | Ki | = | 75.0 | nM | 487.56 | CC(C)[C@@H](C(=O)N[C@H]1CCc2cccc3c2N(C1=O)[C@H](C(=O)NCc1cn[nH]n1)C3)c1ccccn1 | Homo sapiens | CHEMBL684582 | single protein format | |
CHEMBL70602 | Ki | = | 80.0 | nM | 498.53 | CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@H](C=O)CC(=O)O | Homo sapiens | CHEMBL684582 | single protein format | |
CHEMBL71937 | Ki | = | 122.0 | nM | 452.51 | CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@H]1CC[C@H]2CC[C@@H](C(=O)N[C@H](C=O)CC(=O)O)N2C1=O | Homo sapiens | CHEMBL684582 | single protein format | |
CHEMBL69482 | Ki | = | 133.0 | nM | 422.44 | CC[C@H](C)[C@H](NC(C)=O)C(=O)Nc1cccn(CC(=O)N[C@H](C=O)CC(=O)O)c1=O | Homo sapiens | CHEMBL684582 | single protein format | |
CHEMBL69424 | Ki | = | 270.0 | nM | 426.47 | CC[C@H](C)[C@H](NC(C)=O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@H](C=O)CC(=O)O | Homo sapiens | CHEMBL684582 | single protein format | |
CHEMBL305418 | Ki | = | 360.0 | nM | 511.58 | CC[C@H](C)[C@@H](C(=O)N[C@H]1CCc2cccc3c2N(C1=O)[C@H](C(=O)NCc1cc(O)no1)C3)N(C)C(C)=O | Homo sapiens | CHEMBL684582 | single protein format | |
CHEMBL306449 | Ki | = | 580.0 | nM | 486.57 | CC[C@H](C)[C@@H](C(=O)N[C@H]1CCc2cccc3c2N(C1=O)[C@H](C(=O)NCCC(=O)O)C3)N(C)C(C)=O | Homo sapiens | CHEMBL684582 | single protein format |