P0C869 | PA24B_HUMAN | Cytosolic phospholipase A2 beta (PLA2G4B)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00168 | C2 - C2 domain | 11~113 | |
| PF01735 | PLA2_B - Lysophospholipase catalytic domain | 297~503 | |
| PF18695 | cPLA2_C2 - Cytosolic phospholipases A2 C2-domain | 151~244 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL29838 |  |
IC50 | = | 4.0 | nM | 464.58 | O=C(COc1ccc(SCCCCCc2ccccc2)cc1)COc1ccc(C(=O)O)cc1 | Homo sapiens | CHEMBL767151 | single protein format |
| CHEMBL30108 |  |
IC50 | = | 8.0 | nM | 442.55 | CCCCCCCCCCOc1ccc(OCC(=O)COc2ccc(C(=O)O)cc2)cc1 | Homo sapiens | CHEMBL767151 | single protein format |
| CHEMBL26200 |  |
IC50 | = | 17.0 | nM | 456.58 | CCCCCCCCCCOc1ccc(OCC(=O)COc2ccc(CC(=O)O)cc2)cc1 | Homo sapiens | CHEMBL767151 | single protein format |
| CHEMBL286067 |  |
IC50 | = | 20.0 | nM | 487.55 | CCCCCCCCCCOc1ccc(OCC(=O)COc2ccc(C(=O)O)cc2[N+](=O)[O-])cc1 | Homo sapiens | CHEMBL767151 | single protein format |
| CHEMBL418207 |  |
IC50 | = | 26.0 | nM | 470.61 | CCCCCCCCCCCCOc1ccc(OCC(=O)COc2ccc(C(=O)O)cc2)cc1 | Homo sapiens | CHEMBL767152 | single protein format |
| CHEMBL29515 |  |
IC50 | = | 30.0 | nM | 422.56 | CCCCCCCCCCOc1ccc(OCC(=O)COCCCCC(=O)O)cc1 | Homo sapiens | CHEMBL767151 | single protein format |
| CHEMBL286068 |  |
IC50 | = | 35.0 | nM | 456.58 | CCCCCCCCCCOc1ccc(OCC(=O)COCc2cccc(C(=O)O)c2)cc1 | Homo sapiens | CHEMBL767151 | single protein format |
| CHEMBL29353 |  |
IC50 | = | 40.0 | nM | 456.58 | CCCCCCCCCCOc1ccc(OCC(=O)COCc2ccc(C(=O)O)cc2)cc1 | Homo sapiens | CHEMBL767151 | single protein format |
| CHEMBL282164 |  |
IC50 | = | 46.0 | nM | 414.5 | CCCCCCCCOc1ccc(OCC(=O)COc2ccc(C(=O)O)cc2)cc1 | Homo sapiens | CHEMBL767151 | single protein format |
| CHEMBL30130 |  |
IC50 | = | 48.0 | nM | 448.52 | O=C(COc1ccc(OCCCCCc2ccccc2)cc1)COc1ccc(C(=O)O)cc1 | Homo sapiens | CHEMBL767151 | single protein format |
| CHEMBL30107 |  |
IC50 | = | 50.0 | nM | 442.55 | CCCCCCCCCCOc1ccc(OCC(=O)COc2cccc(C(=O)O)c2)cc1 | Homo sapiens | CHEMBL767151 | single protein format |
| CHEMBL29247 |  |
IC50 | = | 60.0 | nM | 456.58 | CCCCCCCCCCOc1ccc(OCC(=O)COc2cccc(CC(=O)O)c2)cc1 | Homo sapiens | CHEMBL767151 | single protein format |
| CHEMBL29246 |  |
IC50 | = | 60.0 | nM | 472.58 | CCCCCCCCCCOc1ccc(OCC(=O)COc2cccc(OCC(=O)O)c2)cc1 | Homo sapiens | CHEMBL767151 | single protein format |
| CHEMBL285344 |  |
IC50 | = | 70.0 | nM | 438.63 | CCCCCCCCCCOc1ccc(OCC(=O)CSCCCCC(=O)O)cc1 | Homo sapiens | CHEMBL767151 | single protein format |
| CHEMBL25900 |  |
IC50 | = | 74.0 | nM | 472.58 | CCCCCCCCCCOc1ccc(OCC(=O)COc2ccc(C(=O)O)cc2OC)cc1 | Homo sapiens | CHEMBL767151 | single protein format |
| CHEMBL27479 |  |
IC50 | = | 150.0 | nM | 424.6 | CCCCCCCCCCOc1ccc(OCC(=O)CSCCCC(=O)O)cc1 | Homo sapiens | CHEMBL767151 | single protein format |
| CHEMBL27245 |  |
IC50 | = | 240.0 | nM | 408.54 | CCCCCCCCCCOc1ccc(OCC(=O)COCCCC(=O)O)cc1 | Homo sapiens | CHEMBL767151 | single protein format |
| CHEMBL25853 |  |
IC50 | = | 270.0 | nM | 410.58 | CCCCCCCCCCOc1ccc(OCC(=O)CSCCC(=O)O)cc1 | Homo sapiens | CHEMBL767151 | single protein format |
| CHEMBL413539 |  |
IC50 | = | 280.0 | nM | 386.44 | CCCCCCOc1ccc(OCC(=O)COc2ccc(C(=O)O)cc2)cc1 | Homo sapiens | CHEMBL767151 | single protein format |
| CHEMBL283294 |  |
IC50 | = | 400.0 | nM | 466.68 | CCCCCCCCCCCCCCOc1ccc(OCC(=O)CSCCC(=O)O)cc1 | Homo sapiens | CHEMBL767151 | single protein format |