P09038 | FGF2_HUMAN | Fibroblast growth factor 2 (FGF2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00167 | FGF - Fibroblast growth factor | 163~282 |
3D structures mapped by conservation among orthologs
[ Domain: "beta-Trefoil" // FGF ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3686884 |  |
IC50 | = | 4.5 | nM | 587.68 | CNC(=O)n1ccc2cc(Oc3ccnc(NC(=O)c4ccc(C5CCN(CCO)CC5)cc4)c3)c(OCCOC)cc21 | Homo sapiens | CHEMBL3706136 | single protein format |
| CHEMBL3686883 |  |
IC50 | = | 5.1 | nM | 557.65 | CNC(=O)n1ccc2cc(Oc3ccnc(NC(=O)c4ccc(C5CCN(C)CC5)cc4)c3)c(OCCOC)cc21 | Homo sapiens | CHEMBL3706136 | single protein format |
| CHEMBL3686864 |  |
IC50 | = | 6.4 | nM | 527.63 | CCN1CCC(c2ccc(C(=O)Nc3cc(Oc4cc5ccn(C(=O)NC)c5cc4OC)ccn3)cc2)CC1 | Homo sapiens | CHEMBL3706136 | single protein format |
| CHEMBL2303729 |  |
IC50 | = | 340.0 | nM | 319.27 | O=C(O)[C@@H]1O[C@@H](OCCN2C(=O)CCC2=O)[C@@H](O)[C@@H](O)[C@@H]1O | Homo sapiens | CHEMBL676959 | single protein format |