P08962 | CD63_HUMAN | CD63 antigen (CD63)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00335 | Tetraspanin - Tetraspanin family | 10~229 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3953841 |  |
IC50 | = | 33.0 | nM | 418.46 | Nc1cncc(-c2cn3ccnc3c(Nc3ccc(N4CCO[C@@H](CO)C4)cc3)n2)n1 | Homo sapiens | CHEMBL3887150 | single protein format |
| CHEMBL3917084 |  |
IC50 | = | 51.0 | nM | 457.54 | Cc1ncc(-c2cn3ccnc3c(Nc3ccc(N4CCN(C5COC5)CC4)cc3)n2)nc1N | Homo sapiens | CHEMBL3887150 | single protein format |
| CHEMBL3986824 |  |
IC50 | = | 80.0 | nM | 443.52 | Nc1cncc(-c2cn3ccnc3c(Nc3ccc(N4CCN(C5COC5)CC4)cc3)n2)n1 | Homo sapiens | CHEMBL3887150 | single protein format |
| CHEMBL5083772 |  |
IC50 | = | 82.0 | nM | 542.65 | Cn1cc(Nc2nccc(-c3ccc4c(c3)CN(C3COC3)CC[C@H]4NC(=O)c3cn(C(C)(C)C)nn3)n2)cn1 | Homo sapiens | CHEMBL5043300 | single protein format |
| CHEMBL3978560 |  |
IC50 | = | 101.0 | nM | 387.45 | Nc1cncc(-c2cn3ccnc3c(Nc3ccc(N4CCOCC4)cc3)n2)c1 | Homo sapiens | CHEMBL3887150 | single protein format |
| CHEMBL3902654 |  |
IC50 | = | 120.0 | nM | 503.57 | Nc1cncc(-c2cn3ccnc3c(Nc3ccc(N4CCN(C5COC5)CC4)c(OCCO)c3)n2)n1 | Homo sapiens | CHEMBL3887150 | single protein format |
| CHEMBL3973635 |  |
IC50 | = | 128.0 | nM | 475.56 | Nc1cncc(-c2cn3ccnc3c(Nc3ccc(N4CCN(CC(CO)CO)CC4)cc3)n2)n1 | Homo sapiens | CHEMBL3887150 | single protein format |
| CHEMBL3929647 |  |
IC50 | = | 157.0 | nM | 457.54 | Cc1c(-c2cncc(N)n2)nc(Nc2ccc(N3CCN(C4COC4)CC3)cc2)c2nccn12 | Homo sapiens | CHEMBL3887150 | single protein format |
| CHEMBL3911668 |  |
IC50 | = | 167.0 | nM | 517.59 | Cc1ncc(-c2cn3ccnc3c(Nc3ccc(N4CCN(C5COC5)CC4)c(OCCO)c3)n2)nc1N | Homo sapiens | CHEMBL3887150 | single protein format |
| CHEMBL3952825 |  |
IC50 | = | 250.0 | nM | 401.47 | Cc1ncc(-c2cn3ccnc3c(Nc3ccc(N4CCOCC4)cc3)n2)cc1N | Homo sapiens | CHEMBL3887150 | single protein format |
| CHEMBL3962740 |  |
IC50 | = | 734.0 | nM | 362.39 | COc1ccc(Nc2nc(-c3ccc(N)nc3)cn3ccnc23)cc1OC | Homo sapiens | CHEMBL3887150 | single protein format |
| CHEMBL3981576 |  |
IC50 | = | 809.0 | nM | 361.41 | COc1ccc(Nc2nc(-c3cccc(N)c3)cn3ccnc23)cc1OC | Homo sapiens | CHEMBL3887150 | single protein format |