P08263 | GSTA1_HUMAN | Glutathione S-transferase A1 (GSTA1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00043 | GST_C - Glutathione S-transferase, C-terminal domain | 100~192 | |
| PF02798 | GST_N - Glutathione S-transferase, N-terminal domain | 6~77 |
3D structures mapped by conservation among orthologs
[ Domain: "Glutathione S-transferase (GST)-C" // GST_C_3 ]
[ Domain: "Thioredoxin-like" // GST_N_5 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3310889 |  |
IC50 | = | 180.0 | nM | 349.18 | CC(=O)N/N=C(/c1ccccc1O)c1cc(Br)ccc1O | Homo sapiens | CHEMBL3369278 | single protein format |
| CHEMBL3310886 |  |
IC50 | = | 180.0 | nM | 290.32 | O=C(c1ccccc1O)c1cc(-c2ccccc2)ccc1O | Homo sapiens | CHEMBL5260871 | single protein format |
| CHEMBL5289853 |  |
IC50 | = | 180.0 | nM | 349.18 | CC(=O)N/N=C(\c1ccccc1O)c1cc(Br)ccc1O | Homo sapiens | CHEMBL5260871 | single protein format |
| CHEMBL3310888 |  |
IC50 | = | 240.0 | nM | 293.12 | O=C(c1ccccc1O)c1cc(Br)ccc1O | Homo sapiens | CHEMBL3369278 | single protein format |
| CHEMBL3310887 |  |
IC50 | = | 330.0 | nM | 332.36 | O=C(NN=C(c1ccccc1O)c1ccccc1O)c1ccccc1 | Homo sapiens | CHEMBL3369278 | single protein format |
| CHEMBL3310888 | |
Ki | = | 360.0 | nM | 293.12 | O=C(c1ccccc1O)c1cc(Br)ccc1O | Homo sapiens | CHEMBL3369280 | single protein format |
| CHEMBL3310887 | |
Ki | = | 380.0 | nM | 332.36 | O=C(NN=C(c1ccccc1O)c1ccccc1O)c1ccccc1 | Homo sapiens | CHEMBL3369280 | single protein format |
| CHEMBL58135 |  |
Ki | = | 840.0 | nM | 391.49 | CCCCCCSCC(NC(=O)CCC(N)C(=O)O)C(=O)NCC(=O)O | Homo sapiens | CHEMBL682616 | single protein format |