P08138 | TNR16_HUMAN | Tumor necrosis factor receptor superfamily member 16 (NGFR)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00020 | TNFR_c6 - TNFR/NGFR cysteine-rich region | 67~107 | |
| PF00020 | TNFR_c6 - TNFR/NGFR cysteine-rich region | 109~146 | |
| PF00020 | TNFR_c6 - TNFR/NGFR cysteine-rich region | 149~188 | |
| PF00531 | Death - Death domain | 345~417 | |
| PF18422 | TNFR_16_TM - Tumor necrosis factor receptor member 16 trans-membrane domain | 246~283 |
3D structures mapped by conservation among orthologs
[ Domain: "DEATH domain" // Death ]
[ Domain: "Transmembrane segment of lysosome-associated membrane glycoprotein 2" // UNK_F_TYPE ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL137953 |  |
IC50 | = | 200.0 | nM | 362.35 | Cn1c2ccc(NC(=O)c3ccccc3)cc2c(=O)n2nc(C(=O)O)cc12 | Homo sapiens | CHEMBL753643 | single protein format |