P07327 | ADH1A_HUMAN | Alcohol dehydrogenase 1A (ADH1A)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00107 | ADH_zinc_N - Zinc-binding dehydrogenase | 203~334 | |
| PF08240 | ADH_N - Alcohol dehydrogenase GroES-like domain | 34~162 |
3D structures mapped by conservation among orthologs
[ Domain: "Alcohol dehydrogenase-like, N-terminal domain" // ADH_N ]
[ Domain: "NAD(P)-binding Rossmann-fold domains" // ADH_zinc_N ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4465918 |  |
IC50 | = | 460.0 | nM | 563.48 | O=C(CCCC(=O)N1C[C@@H](CCl)c2c1cc(O)c1ccccc21)N1C[C@@H](CCl)c2c1cc(O)c1ccccc21 | Homo sapiens | CHEMBL4373595 | single protein format |
| CHEMBL45844 |  |
Ki | = | 360.0 | nM | 167.25 | O=CN(C1CCCC1)C1CCC1 | Homo sapiens | CHEMBL646633 | single protein format |
| CHEMBL45704 |  |
Ki | = | 880.0 | nM | 153.22 | O=CN(C1CCCC1)C1CC1 | Homo sapiens | CHEMBL646633 | single protein format |