P06865 | HEXA_HUMAN | Beta-hexosaminidase subunit alpha (HEXA)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00728 | Glyco_hydro_20 - Glycosyl hydrolase family 20, catalytic domain | 167~487 | |
| PF14845 | Glycohydro_20b2 - beta-acetyl hexosaminidase like | 23~145 |
3D structures mapped by conservation among orthologs
[ Domain: "TIM barrels" // Glyco_hydro_20 ]
[ Domain: "beta-N-acetylhexosaminidase-like domain" // Glycohydro_20b2 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4097052 |  |
IC50 | = | 100.0 | nM | 366.46 | CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)N[C@@H]1COCCCCc1ccccc1 | Homo sapiens | CHEMBL4007597 | single protein format |
| CHEMBL257158 |  |
Ki | = | 270.0 | nM | 219.26 | CC1=N[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]2S1 | Homo sapiens | CHEMBL2388711 | single protein format |