3D structures mapped by conservation among orthologs

[ Domain: "Lipase/lipooxygenase domain (PLAT/LH2 domain)" // PLAT ]

 PyMOL session

[ Domain: "alpha/beta-Hydrolases" // Lipase ]

 PyMOL session

[ Alpha Fold Model ] (go)

Known binders annotated in ChEMBL

 IC50 CSV

Only the first 20 rows are shown.

molecule_chembl_id	structure	assay_type	relation	value	unit	mol_wt	smiles	organism	assay_chembl_id	bao_label
CHEMBL175247		IC50	=	66.0	nM	495.75	CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O	Homo sapiens	CHEMBL4385277	cell-based format
CHEMBL339297		IC50	=	200.0	nM	367.41	COc1nn(-c2ccc(NC(=O)c3ccc(C(C)(C)C)cc3)cc2)c(=O)o1	Homo sapiens	CHEMBL711027	single protein format