P06734 | FCER2_HUMAN | Low affinity immunoglobulin epsilon Fc receptor (FCER2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00059 | Lectin_C - Lectin C-type domain | 181~283 |
3D structures mapped by conservation among orthologs
[ Domain: "C-type lectin-like" // Lectin_C ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL115348 |  |
IC50 | = | 12.0 | nM | 528.68 | CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSC/C(=N/O)c1ccccc1)C(=O)NO | Homo sapiens | CHEMBL655812 | assay format |
| CHEMBL118054 |  |
IC50 | = | 13.0 | nM | 453.56 | COC(=O)CSC[C@H](C(=O)NO)[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O | Homo sapiens | CHEMBL655812 | assay format |
| CHEMBL324564 |  |
IC50 | = | 16.0 | nM | 513.66 | CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSCC(=O)c1ccccc1)C(=O)NO | Homo sapiens | CHEMBL655812 | assay format |
| CHEMBL322050 |  |
IC50 | = | 20.0 | nM | 441.51 | NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cc2ccccc2s1)[C@H](O)C(=O)NO | Homo sapiens | CHEMBL694791 | single protein format |
| CHEMBL432583 |  |
IC50 | = | 20.0 | nM | 401.46 | CC(C)(C)[C@H](NC(=O)[C@H](Cc1ccc2ccccc2c1)[C@H](O)C(=O)NO)C(N)=O | Homo sapiens | CHEMBL694791 | single protein format |
| CHEMBL323228 |  |
IC50 | = | 20.0 | nM | 402.45 | CC(C)(C)[C@H](NC(=O)[C@H](Cc1cnc2ccccc2c1)[C@H](O)C(=O)NO)C(N)=O | Homo sapiens | CHEMBL694791 | single protein format |
| CHEMBL115326 |  |
IC50 | = | 20.0 | nM | 499.63 | CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccccc1)C(N)=O)[C@H](CSCC(=O)c1ccccc1)C(=O)NO | Homo sapiens | CHEMBL655812 | assay format |
| CHEMBL115211 |  |
IC50 | = | 30.0 | nM | 485.65 | CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSCc1ccccc1)C(=O)NO | Homo sapiens | CHEMBL655817 | assay format |
| CHEMBL424251 |  |
IC50 | = | 30.0 | nM | 463.63 | CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccccc1)C(N)=O)[C@H](CSc1cccs1)C(=O)NO | Homo sapiens | CHEMBL655812 | assay format |
| CHEMBL114657 |  |
IC50 | = | 40.0 | nM | 487.62 | CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSc1ccc(O)cc1)C(=O)NO | Homo sapiens | CHEMBL655818 | assay format |
| CHEMBL114427 |  |
IC50 | = | 40.0 | nM | 471.62 | CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSc1ccccc1)C(=O)NO | Homo sapiens | CHEMBL655818 | assay format |
| CHEMBL320799 |  |
IC50 | = | 50.0 | nM | 529.66 | CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSc1ccc(C(=O)OC)cc1)C(=O)NO | Homo sapiens | CHEMBL651875 | assay format |
| CHEMBL326148 |  |
IC50 | = | 60.0 | nM | 549.09 | CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccccc1)C(N)=O)[C@H](CSC/C(=N/O)c1ccc(Cl)cc1)C(=O)NO | Homo sapiens | CHEMBL655812 | assay format |
| CHEMBL2111687 |  |
IC50 | = | 70.0 | nM | 405.5 | CC(C)(C)[C@H](NC(=O)C(C[C@@H]1CCc2ccccc2C1)[C@H](O)C(=O)NO)C(N)=O | Homo sapiens | CHEMBL694791 | single protein format |
| CHEMBL2112477 |  |
IC50 | = | 70.0 | nM | 405.5 | CC(C)(C)[C@H](NC(=O)C(C[C@H]1CCc2ccccc2C1)[C@H](O)C(=O)NO)C(N)=O | Homo sapiens | CHEMBL694791 | single protein format |
| CHEMBL116506 |  |
IC50 | = | 80.0 | nM | 542.7 | CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSC/C(=N/OC)c1ccccc1)C(=O)NO | Homo sapiens | CHEMBL655812 | assay format |
| CHEMBL110713 |  |
IC50 | = | 80.0 | nM | 419.45 | CC(C)(C)[C@H](NC(=O)[C@H](Cc1ccc2ccc(F)cc2c1)[C@H](O)C(=O)NO)C(N)=O | Homo sapiens | CHEMBL694791 | single protein format |
| CHEMBL324205 |  |
IC50 | = | 100.0 | nM | 516.62 | CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSc1ccc([N+](=O)[O-])cc1)C(=O)NO | Homo sapiens | CHEMBL877262 | assay format |
| CHEMBL110546 |  |
IC50 | = | 100.0 | nM | 453.47 | NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc2ccc(F)cc2c1)[C@H](O)C(=O)NO | Homo sapiens | CHEMBL694791 | single protein format |
| CHEMBL320798 |  |
IC50 | = | 100.0 | nM | 529.66 | CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSc1ccccc1C(=O)OC)C(=O)NO | Homo sapiens | CHEMBL655812 | assay format |