P06733 | ENOA_HUMAN | Alpha-enolase (ENO1)

Pfam Domain Table

AccessionDomainRangeColor
PF00113Enolase_C - Enolase, C-terminal TIM barrel domain143~430
PF03952Enolase_N - Enolase, N-terminal domain3~134

3D structures mapped by conservation among orthologs

[ Domain: "Enolase N-terminal domain-like" // Enolase_N ]

 PyMOL session

[ Domain: "TIM barrels" // Enolase_C ]

 PyMOL session


[ Alpha Fold Model ] (go)



Known binders annotated in ChEMBL

 IC50 CSV
Only the first 20 rows are shown.
molecule_chembl_idstructureassay_typerelation valueunitmol_wtsmilesorganism assay_chembl_idbao_label
CHEMBL5185604 IC50 = 1.2 nM 197.08 O=C1C(P(=O)(O)O)CC(O)N1O Homo sapiens CHEMBL5107357 single protein format
CHEMBL5187779 IC50 = 6.3 nM 211.11 C[C@]1(P(=O)(O)O)C[C@H](O)N(O)C1=O Homo sapiens CHEMBL5107357 single protein format
CHEMBL328944 IC50 = 51.0 nM 155.05 O=C(CP(=O)(O)O)NO Homo sapiens CHEMBL5107357 single protein format
CHEMBL260046 IC50 = 301.0 nM 449.04 Cn1c(COP(=O)(NCCBr)NCCBr)cnc1[N+](=O)[O-] Homo sapiens CHEMBL4621998 assay format
CHEMBL3335790 IC50 = 576.0 nM 594.74 NCCOCCOCCNC(=O)Cc1ccc(Nc2nc(NCc3ccc(F)cc3)nc(NCC3CCCCC3)n2)cc1 Homo sapiens CHEMBL3386525 single protein format
CHEMBL4647008 IC50 = 604.0 nM 423.4 CC(C)(C)C(=O)OCOP(=O)(OCOC(=O)C(C)(C)C)C1CCCN(O)C1=O Homo sapiens CHEMBL4621992 assay format