P06702 | S10A9_HUMAN | Protein S100-A9 (S100A9)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01023 | S_100 - S-100/ICaBP type calcium binding domain | 8~51 |
3D structures mapped by conservation among orthologs
[ Domain: "EF-hand" // S_100 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4452496 |  |
IC50 | = | 100.0 | nM | 368.63 | O=S(=O)(Cc1cc(Cl)cc(Cl)c1)Nc1nnc(Cl)cc1O | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4590954 |  |
IC50 | = | 100.0 | nM | 426.3 | CCS(=O)(=O)c1cc(O)c(NS(=O)(=O)Cc2cc(Cl)cc(Cl)c2)nn1 | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4522931 |  |
IC50 | = | 120.0 | nM | 367.64 | O=S(=O)(Cc1cc(Cl)cc(Cl)c1)Nc1ncc(Cl)cc1O | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4440147 |  |
IC50 | = | 120.0 | nM | 358.21 | N#Cc1cnc(NS(=O)(=O)Cc2cc(Cl)cc(Cl)c2)c(O)c1 | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4460770 |  |
IC50 | = | 120.0 | nM | 465.38 | O=S(=O)(Cc1cc(Cl)cc(Cl)c1)Nc1ncc(S(=O)(=O)C2CCCC2)cc1O | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4464961 |  |
IC50 | = | 140.0 | nM | 411.29 | CS(=O)(=O)c1cnc(NS(=O)(=O)Cc2cc(Cl)cc(Cl)c2)c(O)c1 | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4458511 |  |
IC50 | = | 180.0 | nM | 368.63 | O=S(=O)(Cc1cc(Cl)cc(Cl)c1)Nc1nc(Cl)ncc1O | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4579094 |  |
IC50 | = | 250.0 | nM | 413.08 | O=S(=O)(Cc1ccc(Cl)c(Cl)c1)Nc1ncc(Br)nc1O | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4458209 |  |
IC50 | = | 300.0 | nM | 352.17 | O=S(=O)(Cc1cc(F)cc(Cl)c1)Nc1nnc(Cl)cc1O | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4538232 |  |
IC50 | = | 390.0 | nM | 392.65 | N#Cc1nc(NS(=O)(=O)Cc2cc(Cl)cc(Cl)c2)c(O)cc1Cl | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4461753 |  |
IC50 | = | 410.0 | nM | 334.18 | O=S(=O)(Cc1cccc(Cl)c1)Nc1nnc(Cl)cc1O | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4476679 |  |
IC50 | = | 420.0 | nM | 412.28 | CS(=O)(=O)c1cnc(NS(=O)(=O)Cc2cc(Cl)cc(Cl)c2)c(O)n1 | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4442010 |  |
IC50 | = | 530.0 | nM | 445.73 | CS(=O)(=O)c1nc(NS(=O)(=O)Cc2cc(Cl)cc(Cl)c2)c(O)cc1Cl | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4457224 |  |
IC50 | = | 700.0 | nM | 354.6 | O=S(=O)(Nc1nnc(Cl)cc1O)c1cc(Cl)cc(Cl)c1 | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4457635 |  |
IC50 | = | 800.0 | nM | 367.64 | O=S(=O)(Cc1ccc(Cl)c(Cl)c1)Nc1cnc(Cl)cc1O | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4522111 |  |
IC50 | = | 980.0 | nM | 359.19 | N#Cc1ccc(Cl)c(CS(=O)(=O)Nc2nnc(Cl)cc2O)c1 | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4451240 |  |
IC50 | < | 1000.0 | nM | 403.29 | O=S(=O)(Cc1cnc(N2CCCC2)c(Cl)c1)Nc1ccc(Cl)nc1O | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4569952 |  |
IC50 | < | 1000.0 | nM | 364.21 | COc1ncc(CS(=O)(=O)Nc2ccc(Cl)nc2O)cc1Cl | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4448201 |  |
IC50 | < | 1000.0 | nM | 326.8 | CCCc1ccc(S(=O)(=O)Nc2ccc(Cl)nc2O)cc1 | Homo sapiens | CHEMBL4418749 | assay format |
| CHEMBL4463699 |  |
IC50 | < | 1000.0 | nM | 402.09 | O=S(=O)(Cc1cc(Cl)cc(Cl)c1)Nc1cc(Cl)c(Cl)nc1O | Homo sapiens | CHEMBL4418749 | assay format |