P05413 | FABPH_HUMAN | Fatty acid-binding protein, heart (FABP3)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00061 | Lipocalin - Lipocalin / cytosolic fatty-acid binding protein family | 7~132 |
3D structures mapped by conservation among orthologs
[ Domain: "Lipocalins" // Lipocalin_7 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL460750 |  |
IC50 | = | 34.0 | nM | 387.4 | O=C(O)c1cccc2c3c(n(Cc4ccccc4C(F)(F)F)c12)CCCCC3 | Homo sapiens | CHEMBL964128 | single protein format |
| CHEMBL3400905 |  |
IC50 | = | 230.0 | nM | 248.37 | CC(C)c1cc(C(C)C)c(C(=O)O)c(C(C)C)c1 | Homo sapiens | CHEMBL3404793 | single protein format |
| CHEMBL3400157 |  |
IC50 | = | 450.0 | nM | 284.42 | CC(C)c1cc(C(C)C)c(S(=O)(=O)O)c(C(C)C)c1 | Homo sapiens | CHEMBL3404793 | single protein format |
| CHEMBL185595 |  |
IC50 | < | 600.0 | nM | 253.3 | O=C(O)CCCn1c2ccccc2c2ccccc21 | Homo sapiens | CHEMBL830870 | tissue-based format |
| CHEMBL474743 |  |
IC50 | = | 680.0 | nM | 323.37 | O=C(O)c1cccc2c3c(n(Cc4ccccc4F)c12)CCCC3 | Homo sapiens | CHEMBL964126 | single protein format |
| CHEMBL2334261 |  |
IC50 | = | 695.0 | nM | 432.91 | O=C(O)CCCOc1ccccc1-c1cc(-c2ccccc2)n(-c2cccc(Cl)c2)n1 | Homo sapiens | CHEMBL2339129 | single protein format |
| CHEMBL2334256 |  |
IC50 | = | 733.0 | nM | 432.91 | O=C(O)CCCOc1ccccc1-c1cc(-c2ccccc2)n(-c2ccc(Cl)cc2)n1 | Homo sapiens | CHEMBL2339129 | single protein format |
| CHEMBL2334255 |  |
IC50 | = | 733.0 | nM | 477.36 | O=C(O)CCCOc1ccccc1-c1cc(-c2ccccc2)n(-c2ccc(Br)cc2)n1 | Homo sapiens | CHEMBL2339129 | single protein format |
| CHEMBL2334257 |  |
IC50 | = | 787.0 | nM | 440.54 | CC(C)c1ccc(-n2nc(-c3ccccc3OCCCC(=O)O)cc2-c2ccccc2)cc1 | Homo sapiens | CHEMBL2339129 | single protein format |
| CHEMBL4560388 |  |
IC50 | = | 800.0 | nM | 366.81 | Cc1c(Cl)cccc1OCc1cc(=O)n2nc(-c3ccccc3)nc2[nH]1 | Homo sapiens | CHEMBL5262843 | assay format |
| CHEMBL267476 |  |
IC50 | = | 1000.0 | nM | 280.45 | CCCCC/C=C\C/C=C\CCCCCCCC(=O)O | Homo sapiens | CHEMBL1120073 | cell-based format |
| CHEMBL247298 |  |
Ki | = | 4.0 | nM | 476.17 | [3H]c1c(Cl)ccc(COc2cccc(C(=O)O)c2OCc2ccc(Cl)c([3H])c2Cl)c1Cl | Homo sapiens | CHEMBL887935 | single protein format |
| CHEMBL116533 |  |
Ki | = | 32.0 | nM | 413.47 | O=C(O)CCCCOc1ccccc1-c1nc(-c2ccccc2)c(-c2ccccc2)o1 | Homo sapiens | CHEMBL887935 | single protein format |
| CHEMBL1738980 |  |
Ki | = | 93.0 | nM | 297.74 | Cc1nc2ccc(Cl)cc2c(-c2ccccc2)c1C(=O)O | Homo sapiens | CHEMBL3861357 | single protein format |
| CHEMBL3950316 |  |
Ki | = | 100.0 | nM | 380.88 | Cc1cc(Cl)cc2c(-c3ccccc3)c(C(=O)O)c(N3CCCCC3)nc12 | Homo sapiens | CHEMBL3861357 | single protein format |
| CHEMBL394440 |  |
Ki | = | 110.0 | nM | 444.53 | CCc1c(-c2ccccc2)c(-c2ccccc2)nn1-c1ccccc1-c1cccc(C(=O)O)c1 | Homo sapiens | CHEMBL887935 | single protein format |
| CHEMBL5287034 |  |
Ki | = | 150.0 | nM | 311.77 | CCc1nc2ccc(Cl)cc2c(-c2ccccc2)c1C(=O)O | Homo sapiens | CHEMBL5253220 | single protein format |
| CHEMBL247529 |  |
Ki | = | 220.0 | nM | 474.56 | CCc1c(-c2ccccc2-c2cccc(OCC(=O)O)c2)oc(-c2ccccc2)c1-c1ccccc1 | Homo sapiens | CHEMBL887935 | single protein format |
| CHEMBL247920 |  |
Ki | = | 250.0 | nM | 474.56 | CCc1c(-c2ccccc2)c(-c2ccccc2)nn1-c1ccccc1-c1cccc(OCC(=O)O)c1 | Homo sapiens | CHEMBL887935 | single protein format |
| CHEMBL4644782 |  |
Ki | = | 350.0 | nM | 363.8 | O=C(O)c1ccccc1Nc1cccc(Cl)c1-c1ccc2occc2c1 | Homo sapiens | CHEMBL4605258 | assay format |