P05362 | ICAM1_HUMAN | Intercellular adhesion molecule 1 (ICAM1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF03921 | ICAM_N - Intercellular adhesion molecule (ICAM), N-terminal domain | 25~115 | |
| PF13895 | Ig_2 - Immunoglobulin domain | 313~389 | |
| PF21146 | ICAM1_3_5_D2 - ICAM-1/3/5, D2 domain | 219~308 |
3D structures mapped by conservation among orthologs
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // ICAM_N ]
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // I-set_4 ]
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // C1-set_like ]
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // C1-set ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL119501 |  |
IC50 | = | 1.0 | nM | 352.34 | CNC(=O)c1cc2c(Oc3ccc(C(F)(F)F)cc3)cncc2s1 | Homo sapiens | CHEMBL698938 | cell-based format |
| CHEMBL118113 |  |
IC50 | = | 1.4 | nM | 384.46 | NC(=O)c1cc2c(Oc3ccc(COC4CCCCO4)cc3)cncc2s1 | Homo sapiens | CHEMBL698938 | cell-based format |
| CHEMBL119733 |  |
IC50 | = | 2.0 | nM | 296.35 | C=Cc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 | Homo sapiens | CHEMBL698938 | cell-based format |
| CHEMBL117198 |  |
IC50 | = | 2.0 | nM | 295.32 | N#Cc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 | Homo sapiens | CHEMBL698938 | cell-based format |
| CHEMBL119039 |  |
IC50 | = | 4.0 | nM | 350.4 | CNC(=O)c1cc2c(Oc3ccc(-n4cccn4)cc3)cncc2s1 | Homo sapiens | CHEMBL698938 | cell-based format |
| CHEMBL116152 |  |
IC50 | = | 4.0 | nM | 396.21 | NC(=O)c1cc2c(Oc3ccc(I)cc3)cncc2s1 | Homo sapiens | CHEMBL698938 | cell-based format |
| CHEMBL117746 |  |
IC50 | = | 4.0 | nM | 402.47 | COCCOCCOCc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 | Homo sapiens | CHEMBL698938 | cell-based format |
| CHEMBL116070 |  |
IC50 | = | 5.0 | nM | 349.21 | NC(=O)c1cc2c(Oc3ccc(Br)cc3)cncc2s1 | Homo sapiens | CHEMBL698938 | cell-based format |
| CHEMBL118034 |  |
IC50 | = | 5.0 | nM | 350.4 | CNC(=O)c1cc2c(Oc3ccc(-c4ccco4)cc3)cncc2s1 | Homo sapiens | CHEMBL698938 | cell-based format |
| CHEMBL117279 |  |
IC50 | = | 5.0 | nM | 416.5 | CNC(=O)c1cc2c(Oc3ccc(COCCOCCOC)cc3)cncc2s1 | Homo sapiens | CHEMBL698938 | cell-based format |
| CHEMBL326271 |  |
IC50 | = | 5.0 | nM | 363.24 | CNC(=O)c1cc2c(Oc3ccc(Br)cc3)cncc2s1 | Homo sapiens | CHEMBL698938 | cell-based format |
| CHEMBL326120 |  |
IC50 | = | 5.0 | nM | 336.38 | NC(=O)c1cc2c(Oc3ccc(-n4ccnc4)cc3)cncc2s1 | Homo sapiens | CHEMBL698938 | cell-based format |
| CHEMBL325184 |  |
IC50 | = | 6.0 | nM | 350.4 | CNC(=O)c1cc2c(Oc3ccc(-n4ccnc4)cc3)cncc2s1 | Homo sapiens | CHEMBL698938 | cell-based format |
| CHEMBL117668 |  |
IC50 | = | 6.0 | nM | 358.42 | COCCOCc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 | Homo sapiens | CHEMBL698938 | cell-based format |
| CHEMBL117894 |  |
IC50 | = | 6.0 | nM | 366.47 | CNC(=O)c1cc2c(Oc3ccc(-c4cccs4)cc3)cncc2s1 | Homo sapiens | CHEMBL698938 | cell-based format |
| CHEMBL331584 |  |
IC50 | = | 8.0 | nM | 372.45 | CNC(=O)c1cc2c(Oc3ccc(COCCOC)cc3)cncc2s1 | Homo sapiens | CHEMBL698938 | cell-based format |
| CHEMBL267125 |  |
IC50 | = | 8.0 | nM | 314.44 | Cc1ccc(Sc2cncc3sc(C(N)=O)cc23)cc1C | Homo sapiens | CHEMBL697203 | cell-based format |
| CHEMBL118518 |  |
IC50 | = | 9.0 | nM | 304.76 | NC(=O)c1cc2c(Oc3ccc(Cl)cc3)cncc2s1 | Homo sapiens | CHEMBL698938 | cell-based format |
| CHEMBL266198 |  |
IC50 | = | 10.0 | nM | 365.28 | NC(=O)c1cc2c(Sc3ccc(Br)cc3)cncc2s1 | Homo sapiens | CHEMBL697203 | cell-based format |
| CHEMBL118886 |  |
IC50 | = | 10.0 | nM | 322.75 | NC(=O)c1cc2c(Oc3ccc(Cl)c(F)c3)cncc2s1 | Homo sapiens | CHEMBL698938 | cell-based format |