P04798 | CP1A1_HUMAN | Cytochrome P450 1A1 (CYP1A1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00067 | p450 - Cytochrome P450 | 40~491 |
3D structures mapped by conservation among orthologs
[ Domain: "Cytochrome P450" // p450 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL283196 |  |
IC50 | = | 10.0 | nM | 272.3 | O=c1cc(-c2ccccc2)oc2c1ccc1ccccc12 | Homo sapiens | CHEMBL4057734 | assay format |
| CHEMBL224157 |  |
IC50 | = | 20.0 | nM | 262.26 | O=c1cc(-c2ccccc2)oc2c1ccc1occc12 | Homo sapiens | CHEMBL4675252 | cell-based format |
| CHEMBL577397 |  |
IC50 | = | 20.0 | nM | 336.3 | COc1c(-c2ccc3c(c2)OCO3)oc2c(ccc3occc32)c1=O | Homo sapiens | CHEMBL4675252 | cell-based format |
| CHEMBL140796 |  |
IC50 | = | 20.0 | nM | 246.22 | COc1c2ccoc2c(OC)c2oc(=O)ccc12 | Homo sapiens | CHEMBL4257972 | cell-based format |
| CHEMBL208484 |  |
IC50 | = | 30.0 | nM | 292.29 | COc1c(-c2ccccc2)oc2c(ccc3occc32)c1=O | Homo sapiens | CHEMBL4675252 | cell-based format |
| CHEMBL4282750 |  |
IC50 | = | 30.0 | nM | 292.29 | COc1c(-c2ccccc2)oc2c(ccc3ccoc32)c1=O | Homo sapiens | CHEMBL4257972 | cell-based format |
| CHEMBL4447260 |  |
IC50 | = | 41.0 | nM | 326.42 | COc1cc(/C=C/c2cccs2)cc(OCCn2ccnc2)c1 | Homo sapiens | CHEMBL4330008 | cell membrane format |
| CHEMBL42428 |  |
IC50 | = | 61.0 | nM | 246.33 | COc1cc(/C=C/c2cccs2)cc(OC)c1 | Homo sapiens | CHEMBL4330008 | cell membrane format |
| CHEMBL4218749 |  |
IC50 | = | 61.0 | nM | 299.33 | COc1cc(/C=C/C(=O)c2ccncc2)cc(OC)c1OC | Homo sapiens | CHEMBL4181947 | cell membrane format |
| CHEMBL4205073 |  |
IC50 | = | 63.0 | nM | 313.35 | CCOc1cc(/C=C/C(=O)c2ccncc2)cc(OC)c1OC | Homo sapiens | CHEMBL4181956 | cell-based format |
| CHEMBL4210137 |  |
IC50 | = | 65.0 | nM | 327.38 | CCOc1cc(/C=C/C(=O)c2ccncc2)cc(OC)c1OCC | Homo sapiens | CHEMBL4181956 | cell-based format |
| CHEMBL24171 |  |
IC50 | = | 80.0 | nM | 216.19 | COc1c2ccoc2cc2oc(=O)ccc12 | Homo sapiens | CHEMBL4257972 | cell-based format |
| CHEMBL4211876 |  |
IC50 | = | 92.0 | nM | 341.41 | CCOc1cc(/C=C/C(=O)c2ccncc2)cc(OCC)c1OCC | Homo sapiens | CHEMBL4181956 | cell-based format |
| CHEMBL4214111 |  |
IC50 | = | 220.0 | nM | 269.3 | COc1cc(/C=C/C(=O)c2ccncc2)cc(OC)c1 | Homo sapiens | CHEMBL4181956 | cell-based format |
| CHEMBL3132928 |  |
IC50 | = | 230.0 | nM | 300.35 | COc1ccc(/C=C/c2c(OC)cccc2OC)cc1OC | Homo sapiens | CHEMBL3137186 | single protein format |
| CHEMBL4763663 |  |
IC50 | = | 240.0 | nM | 278.26 | O=c1cc(-c2cccc(O)c2)oc2c1ccc1occc12 | Homo sapiens | CHEMBL4675252 | cell-based format |
| CHEMBL3132931 |  |
IC50 | = | 270.0 | nM | 330.38 | COc1cc(OC)c(/C=C/c2ccc(OC)c(OC)c2)c(OC)c1 | Homo sapiens | CHEMBL3137186 | single protein format |
| CHEMBL4213815 |  |
IC50 | = | 280.0 | nM | 313.35 | CCOc1c(OC)cc(/C=C/C(=O)c2ccncc2)cc1OC | Homo sapiens | CHEMBL4181956 | cell-based format |
| CHEMBL46909 |  |
IC50 | = | 300.0 | nM | 300.35 | COc1cc(/C=C/c2ccc(OC)cc2OC)cc(OC)c1 | Homo sapiens | CHEMBL4330008 | cell membrane format |
| CHEMBL3132924 |  |
IC50 | = | 360.0 | nM | 270.33 | COc1ccccc1/C=C/c1ccc(OC)c(OC)c1 | Homo sapiens | CHEMBL3137186 | single protein format |