P04406 | G3P_HUMAN | Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00044 | Gp_dh_N - Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain | 4~104 | |
| PF02800 | Gp_dh_C - Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain | 157~314 |
3D structures mapped by conservation among orthologs
[ Domain: "Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain" // Gp_dh_C ]
[ Domain: "NAD(P)-binding Rossmann-fold domains" // Gp_dh_N_2 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3142964 |  |
IC50 | = | 300.0 | nM | 400.4 | COc1cccc(C(=O)N[C@@H]2[C@H](O)[C@@H](CO)O[C@H]2n2cnc3c(N)ncnc32)c1 | Homo sapiens | CHEMBL684048 | single protein format |
| CHEMBL256155 |  |
IC50 | = | 590.0 | nM | 250.25 | O=C1C=C(Oc2ccccc2)C(=O)c2ccccc21 | Homo sapiens | CHEMBL3606220 | single protein format |
| CHEMBL124807 |  |
IC50 | = | 600.0 | nM | 349.37 | Nc1ncnc2c1nc(-c1cccs1)n2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O | Homo sapiens | CHEMBL684056 | single protein format |