P04233 | HG2A_HUMAN | HLA class II histocompatibility antigen gamma chain (CD74)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00086 | Thyroglobulin_1 | 224–269 | |
| PF08831 | MHCassoc_trimer | 136–203 | |
| PF09307 | MHC2-interact | 17–128 |
3D structures mapped by conservation among orthologs
[ Domain: "Class II MHC-associated invariant chain ectoplasmic trimerization domain" // UNK_F_TYPE ]
[ Domain: "Thyroglobulin type-1 domain" // Thyroglobulin_1 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL206745 |  |
IC50 | = | 810.0 | nM | 581.64 | CC(=O)N1CCc2c(c(-c3ccc(C(F)(F)F)cc3)nn2CCCN2CCC(N3C(=O)COc4ccccc43)CC2)C1 | Homo sapiens | CHEMBL865649 | single protein format |