P03905 | NU4M_HUMAN | NADH-ubiquinone oxidoreductase chain 4 (MT-ND4)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00361 | Proton_antipo_M - NADH:quinone oxidoreductase/Mrp antiporter, TM | 112~397 | |
| PF01059 | Oxidored_q5_N - NADH-ubiquinone oxidoreductase chain 4, amino terminus | 1~109 |
3D structures mapped by conservation among orthologs
[ Domain: "NADH-quinone oxidoreductase subunit L (NuoL)-related" // Proton_antipo_M ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL429023 |  |
IC50 | = | 3.5 | nM | 394.42 | C=C(C)[C@H]1Cc2c(ccc3c2O[C@@H]2COc4cc(OC)c(OC)cc4[C@@H]2C3=O)O1 | Homo sapiens | CHEMBL747976 | single protein format |
| CHEMBL154388 |  |
IC50 | = | 16.0 | nM | 410.47 | COc1cc2c(cc1OC)[C@]1(C)C(=O)c3ccc4c(c3O[C@@H]1CO2)C[C@H](C(C)C)O4 | Homo sapiens | CHEMBL747976 | single protein format |
| CHEMBL347114 |  |
IC50 | = | 17.0 | nM | 408.45 | C=C(C)[C@H]1Cc2c(ccc3c2O[C@@H]2COc4cc(OC)c(OC)cc4[C@]2(C)C3=O)O1 | Homo sapiens | CHEMBL747976 | single protein format |
| CHEMBL357929 |  |
IC50 | = | 80.0 | nM | 406.43 | C=C(C)[C@H]1Cc2c(ccc3c2OC24COc5cc(OC)c(OC)cc5C2(C4)C3=O)O1 | Homo sapiens | CHEMBL747976 | single protein format |