P02748 | CO9_HUMAN | Complement component C9 (C9)

Pfam Domain Table

AccessionDomainRangeColor
PF00057Ldl_recept_a - Low-density lipoprotein receptor domain class A100~134
PF00090TSP_1 - Thrombospondin type 1 domain46~94
PF01823MACPF - MAC/Perforin domain274~501

3D structures mapped by conservation among orthologs

[ Domain: "Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains" // MACPF ]

 PyMOL session

[ Domain: "EGF/Laminin" // hEGF_4 ]

 PyMOL session

[ Domain: "LDL receptor-like module" // Ldl_recept_a ]

 PyMOL session

[ Domain: "TSP-1 type 1 repeat" // TSP_1_1 ]

 PyMOL session


[ Alpha Fold Model ] (go)



Known binders annotated in ChEMBL

 IC50 CSV
Only the first 20 rows are shown.
molecule_chembl_idstructureassay_typerelation valueunitmol_wtsmilesorganism assay_chembl_idbao_label
CHEMBL4242254 IC50 = 500.0 nM 572.48 O=C(O)C1=C/C(=C\c2cc(C(c3ccc(O)c(C(=O)O)c3)c3ccc(O)c(C(=O)O)c3)cc(C(=O)O)c2O)C=CC1=O Homo sapiens CHEMBL4229706 single protein format
CHEMBL275938 IC50 = 500.0 nM 422.35 O=C(O)C1=CC(=C(c2ccc(O)c(C(=O)O)c2)c2ccc(O)c(C(=O)O)c2)C=CC1=O Homo sapiens CHEMBL4229706 single protein format