P02708 | ACHA_HUMAN | Acetylcholine receptor subunit alpha (CHRNA1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF02931 | Neur_chan_LBD - Neurotransmitter-gated ion-channel ligand binding domain | 24~230 | |
| PF02932 | Neur_chan_memb - Neurotransmitter-gated ion-channel transmembrane region | 238~446 |
3D structures mapped by conservation among orthologs
[ Domain: "Nicotinic receptor ligand binding domain-like" // Neur_chan_LBD ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL6623 |  |
IC50 | = | 160.0 | nM | 208.69 | Clc1ccc(C2CC3CCC2N3)cn1 | Homo sapiens | CHEMBL3076138 | cell-based format |
| CHEMBL3341967 |  |
Ki | = | 944.0 | nM | 211.7 | Clc1cncc(N2CCCNCC2)c1 | Homo sapiens | CHEMBL3365586 | single protein format |