P01911 | DRB1_HUMAN | HLA class II histocompatibility antigen, DRB1 beta chain (HLA-DRB1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00969 | MHC_II_beta - Class II histocompatibility antigen, beta domain | 43~115 | |
| PF07654 | C1-set - Immunoglobulin C1-set domain | 128~208 |
3D structures mapped by conservation among orthologs
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // C1-set_2 ]
[ Domain: "MHC antigen-recognition domain" // MHC_II_beta ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL79117 |  |
IC50 | = | 1.4 | nM | 525.69 | CCOC(=O)N[C@H](CC1CCCCC1)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O)C(C)C | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL311245 |  |
IC50 | = | 12.0 | nM | 517.63 | CCOC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@H]1CCCCNC1=O)C(C)C | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL80597 |  |
IC50 | = | 17.0 | nM | 563.7 | CCOC(=O)N[C@H](Cc1ccc(OCC)cc1)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O)C(C)C | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL77558 |  |
IC50 | = | 19.0 | nM | 554.09 | CCOC(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O)C(C)C | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL81463 |  |
IC50 | = | 22.0 | nM | 518.66 | CCNC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O)C(C)C | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL79058 |  |
IC50 | = | 23.0 | nM | 575.73 | CCOC(=O)N[C@H](Cc1csc2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O)C(C)C | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL80852 |  |
IC50 | = | 25.0 | nM | 545.68 | CC(=O)CCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O)C(C)C | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL78426 |  |
IC50 | = | 28.0 | nM | 519.64 | CCOC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O)C(C)C | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL420761 |  |
IC50 | = | 32.0 | nM | 575.75 | CCCCCCOC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O)C(C)C | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL80345 |  |
IC50 | = | 43.0 | nM | 547.7 | CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(C)C)C(N)=O | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL309641 |  |
IC50 | = | 46.0 | nM | 549.67 | CCOC(=O)N[C@H](Cc1ccc(OC)cc1)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O)C(C)C | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL310163 |  |
IC50 | = | 46.0 | nM | 547.65 | CC(=O)OCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O)C(C)C | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL310312 |  |
IC50 | = | 67.0 | nM | 548.69 | CCOC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL310625 |  |
IC50 | = | 81.0 | nM | 546.67 | CC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O)C(C)C | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL78541 |  |
IC50 | = | 81.0 | nM | 548.69 | CCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCC)C(N)=O | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL309610 |  |
IC50 | = | 140.0 | nM | 564.64 | CCOC(=O)N[C@H](Cc1ccc([N+](=O)[O-])cc1)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O)C(C)C | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL76898 |  |
IC50 | = | 140.0 | nM | 531.7 | CCCCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O)C(C)C | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL311939 |  |
IC50 | = | 160.0 | nM | 533.67 | CCOC(=O)N[C@H](CCc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(N)=O)C(C)C | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL420380 |  |
IC50 | = | 170.0 | nM | 560.74 | CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CCCCCN)C(C)C)C(N)=O | Homo sapiens | CHEMBL800187 | single protein format |
| CHEMBL80176 |  |
IC50 | = | 230.0 | nM | 566.73 | CCOC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCSC)C(N)=O | Homo sapiens | CHEMBL800187 | single protein format |