P01730 | CD4_HUMAN | T-cell surface glycoprotein CD4 (CD4)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00047 | ig | 29–119 | |
| PF05790 | C2-set | 126–202 | |
| PF05790 | C2-set | 317–389 | |
| PF09191 | CD4-extracel | 206–316 | |
| PF12104 | Tcell_CD4_C | 426–453 |
3D structures mapped by conservation among orthologs
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // C2-set ]
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // CD4-extracel ]
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // V-set_9 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL1852155 |  |
IC50 | = | 210.0 | nM | 581.8 | C=C1CN(S(=O)(=O)c2ccc(C)cc2)CCCN(Cc2ccccc2)CCCN(S(=O)(=O)c2ccc(C)cc2)C1 | Homo sapiens | CHEMBL4629040 | cell-based format |
| CHEMBL4755141 |  |
IC50 | = | 860.0 | nM | 590.21 | C=C1CN(S(=O)(=O)c2ccc(C)cc2)CCc2cc(CC)cc(n2)CCN(S(=O)(=O)c2ccc(C)cc2)C1.Cl | Homo sapiens | CHEMBL4677392 | cell-based format |