O95718 | ERR2_HUMAN | Steroid hormone receptor ERR2 (ESRRB)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00104 | Hormone_recep - Ligand-binding domain of nuclear hormone receptor | 241~415 | |
| PF00105 | zf-C4 - Double treble clef zinc finger, C4 type | 102~170 |
3D structures mapped by conservation among orthologs
[ Domain: "LIM domain-like" // zf-C4 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL135 |  |
IC50 | = | 3.2 | nM | 272.39 | C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@@H]2O | Homo sapiens | CHEMBL886439 | single protein format |
| CHEMBL4071073 |  |
IC50 | = | 10.0 | nM | 443.59 | CC(=O)Oc1ccc(/C(=C(/c2ccccc2)C(C)C)c2ccc(OCCN(C)C)cc2)cc1 | Homo sapiens | CHEMBL3999513 | cell-based format |
| CHEMBL2326072 |  |
IC50 | = | 19.1 | nM | 493.69 | C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCC#Cc4ccc(-n5cccc5)cc4)[C@H]3[C@@H]1CC[C@@H]2O | Homo sapiens | CHEMBL2330135 | single protein format |
| CHEMBL2326068 |  |
IC50 | = | 41.2 | nM | 543.71 | C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCc4cn(CC5COc6ccccc6O5)nn4)[C@H]3[C@@H]1CC[C@@H]2O | Homo sapiens | CHEMBL2330135 | single protein format |
| CHEMBL4100590 |  |
IC50 | = | 50.0 | nM | 459.59 | COC(=O)C(C)C/C(=C(\c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1 | Homo sapiens | CHEMBL3999513 | cell-based format |
| CHEMBL250097 |  |
IC50 | = | 56.0 | nM | 344.16 | Oc1ccc2c(c1)OCc1c-2nc2ccc(O)cc2c1Br | Homo sapiens | CHEMBL886439 | single protein format |
| CHEMBL402491 |  |
IC50 | = | 88.0 | nM | 299.71 | Oc1ccc2c(c1)OCc1c-2nc2ccc(O)cc2c1Cl | Homo sapiens | CHEMBL886439 | single protein format |
| CHEMBL402492 |  |
IC50 | = | 98.0 | nM | 290.28 | N#Cc1c2c(nc3ccc(O)cc13)-c1ccc(O)cc1OC2 | Homo sapiens | CHEMBL886439 | single protein format |
| CHEMBL2326070 |  |
IC50 | = | 111.9 | nM | 555.68 | C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCc4cn(-c5cc6ccc(O)cc6oc5=O)nn4)[C@H]3[C@@H]1CC[C@@H]2O | Homo sapiens | CHEMBL2330135 | single protein format |
| CHEMBL2326073 |  |
IC50 | = | 120.7 | nM | 478.68 | C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCC#Cc4ccc5ccccc5c4)[C@H]3[C@@H]1CC[C@@H]2O | Homo sapiens | CHEMBL2330135 | single protein format |
| CHEMBL2326076 |  |
IC50 | = | 185.0 | nM | 542.72 | CCOC(=O)CC(=O)c1ccc(C#CCCCC[C@@H]2Cc3cc(O)ccc3[C@H]3CC[C@]4(C)[C@@H](O)CC[C@H]4[C@H]23)cc1 | Homo sapiens | CHEMBL2330135 | single protein format |
| CHEMBL4092854 |  |
IC50 | = | 210.0 | nM | 401.55 | CC(C)/C(=C(\c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1 | Homo sapiens | CHEMBL3999513 | cell-based format |
| CHEMBL198411 |  |
IC50 | = | 212.0 | nM | 316.15 | Oc1ccc(-c2cc(Br)c3cc(O)ccc3n2)cc1 | Homo sapiens | CHEMBL886439 | single protein format |
| CHEMBL372783 |  |
IC50 | = | 213.0 | nM | 271.7 | Oc1ccc(-c2cc(Cl)c3cc(O)ccc3n2)cc1 | Homo sapiens | CHEMBL886439 | single protein format |
| CHEMBL4085105 |  |
IC50 | = | 300.0 | nM | 388.46 | COC(=O)C(C)CC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1ccccc1 | Homo sapiens | CHEMBL3999513 | cell-based format |
| CHEMBL2326074 |  |
IC50 | = | 331.1 | nM | 495.66 | C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCC#Cc4ccc(-c5ccno5)cc4)[C@H]3[C@@H]1CC[C@@H]2O | Homo sapiens | CHEMBL2330135 | single protein format |
| CHEMBL4084142 |  |
IC50 | = | 350.0 | nM | 445.56 | COC(=O)CC/C(=C(\c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1 | Homo sapiens | CHEMBL3999513 | cell-based format |
| CHEMBL44 |  |
IC50 | = | 395.0 | nM | 270.24 | O=c1c(-c2ccc(O)cc2)coc2cc(O)cc(O)c12 | Homo sapiens | CHEMBL886439 | single protein format |
| CHEMBL197667 |  |
IC50 | = | 455.0 | nM | 262.27 | N#Cc1cc(-c2ccc(O)cc2)nc2ccc(O)cc12 | Homo sapiens | CHEMBL886439 | single protein format |
| CHEMBL250302 |  |
IC50 | = | 504.0 | nM | 375.81 | Oc1ccc2c(c1)OCc1c-2nc2ccc(O)cc2c1-c1cccc(Cl)c1 | Homo sapiens | CHEMBL886439 | single protein format |