O95630 | STABP_HUMAN | STAM-binding protein (STAMBP)

Pfam Domain Table

AccessionDomainRangeColor
PF01398JAB - JAB1/Mov34/MPN/PAD-1 ubiquitin protease253~361
PF08969USP8_dimer - USP8 dimerisation domain13~116

3D structures mapped by conservation among orthologs

[ Domain: "USP8 N-terminal domain-like" // USP8_dimer ]

 PyMOL session

[ Domain: "Cytidine deaminase-like" // JAB_1 ]

 PyMOL session


[ Alpha Fold Model ] (go)



Known binders annotated in ChEMBL

 IC50 CSV
Only the first 20 rows are shown.
molecule_chembl_idstructureassay_typerelation valueunitmol_wtsmilesorganism assay_chembl_idbao_label
CHEMBL4586347 IC50 = 330.0 nM 504.61 O=C(CSc1nc2ccc(N3CCOCC3)cc2c(=O)n1CCc1ccccc1)NCc1ccco1 Homo sapiens CHEMBL4356418 cell-based format
CHEMBL4104719 IC50 = 500.0 nM 588.72 O=C(NCc1ccncc1)c1cnc2c(SSc3cccc4cc(C(=O)NCc5ccncc5)cnc34)cccc2c1 Homo sapiens CHEMBL4049711 single protein format
CHEMBL4095913 IC50 = 900.0 nM 566.66 O=C(NCc1ccco1)c1cnc2c(SSc3cccc4cc(C(=O)NCc5ccco5)cnc34)cccc2c1 Homo sapiens CHEMBL4049711 single protein format