O95622 | ADCY5_HUMAN | Adenylate cyclase type 5 (ADCY5)

Helixβ‑strandTurn secondary structure

Pfam Domain Table

AccessionDomainRangeColor
PF00211Guanylate_cyc460–621
PF00211Guanylate_cyc1063–1256
PF06327Adcy_cons_dom669–761
PF16214AC_N1–458

 3D structures mapped by conservation among orthologs


 [ Alpha Fold Model ] (go)



 Known binders annotated in ChEMBL

 IC50 CSV
Only the first 20 rows are shown.
molecule_chembl_idstructureassay_typerelation valueunitmol_wtsmilesorganism assay_chembl_idbao_label
CHEMBL432908 IC50 = 200.0 nM 262.27 Nc1ncnc2c1ncn2[C@H]1CC[C@H](C(=O)NO)C1 Homo sapiens CHEMBL645674 cell-based format
CHEMBL69185 IC50 = 400.0 nM 274.28 Nc1ncnc2c1ncn2[C@H]1C=C[C@H](CC(=O)NO)C1 Homo sapiens CHEMBL645674 cell-based format
CHEMBL69184 IC50 = 600.0 nM 276.3 Nc1ncnc2c1ncn2[C@@H]1CC[C@@H](CC(=O)NO)C1 Homo sapiens CHEMBL645674 cell-based format