O95398 | RPGF3_HUMAN | Rap guanine nucleotide exchange factor 3 (RAPGEF3)

Helixβ‑strandTurn secondary structure

Pfam Domain Table

AccessionDomainRangeColor
PF00027cNMP_binding268–347
PF00610DEP116–184
PF00617RasGEF665–843
PF00618RasGEF_N387–492

 3D structures mapped by conservation among orthologs


 [ Alpha Fold Model ] (go)



 Known binders annotated in ChEMBL

 IC50 CSV
Only the first 20 rows are shown.
molecule_chembl_idstructureassay_typerelation valueunitmol_wtsmilesorganism assay_chembl_idbao_label
CHEMBL4517829 IC50 = 900.0 nM 416.46 COc1ccc2ccc(OCC(=O)NS(=O)(=O)c3ccc(N)cc3OC)cc2c1 Homo sapiens CHEMBL4346467 assay format