O95363 | SYFM_HUMAN | Phenylalanine--tRNA ligase, mitochondrial (FARS2)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01409 | tRNA-synt_2d | 76–198 | |
| PF01409 | tRNA-synt_2d | 242–343 | |
| PF03147 | FDX-ACB | 358–450 |
3D structures mapped by conservation among orthologs
[ Domain: "Anticodon-binding domain of PheRS" // FDX-ACB ]
[ Domain: "Class II aaRS and biotin synthetases" // tRNA-synt_2d ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL281860 |  |
IC50 | = | 170.0 | nM | 496.35 | O=C(Nc1ccc(Cl)c(Cl)c1)[C@H]1[C@H](c2ccccc2)O[C@@]23[C@@H](O)c4ccccc4[C@@H]2OC(=O)[C@@H]13 | Homo sapiens | CHEMBL768844 | single protein format |
| CHEMBL284654 |  |
IC50 | = | 470.0 | nM | 496.35 | O=C(Nc1ccc(Cl)c(Cl)c1)[C@H]1[C@H](c2ccccc2)O[C@@]23[C@H](O)c4ccccc4[C@@H]2OC(=O)[C@@H]13 | Homo sapiens | CHEMBL768844 | single protein format |