O95136 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor 2 (S1PR2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 50~288 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL225155 |  |
IC50 | = | 0.23 | nM | 379.48 | CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(=O)(O)O | Homo sapiens | CHEMBL807599 | cell-based format |
| CHEMBL114606 |  |
IC50 | = | 0.77 | nM | 387.46 | CCCCCCCCc1ccc(CCC(N)(CO)COP(=O)(O)O)cc1 | Homo sapiens | CHEMBL807599 | cell-based format |
| CHEMBL119440 |  |
IC50 | = | 0.8 | nM | 385.49 | CCCCCCCCOc1c(C)cc(CNCCCP(=O)(O)O)cc1C | Homo sapiens | CHEMBL807597 | cell-based format |
| CHEMBL117130 |  |
IC50 | = | 0.8 | nM | 373.43 | CCCCCCCCc1ccc(CCC(N)(CO)OP(=O)(O)O)cc1 | Homo sapiens | CHEMBL807596 | cell-based format |
| CHEMBL119116 |  |
IC50 | = | 1.0 | nM | 426.32 | CCCCCCCCOc1c(Cl)cc(CNCCCP(=O)(O)O)cc1Cl | Homo sapiens | CHEMBL807597 | cell-based format |
| CHEMBL119382 |  |
IC50 | = | 1.4 | nM | 395.44 | CCCCCCCn1nnc(-c2ccc(CNCCCP(=O)(O)O)cc2)n1 | Homo sapiens | CHEMBL807597 | cell-based format |
| CHEMBL441826 |  |
IC50 | = | 1.5 | nM | 494.41 | CCCCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC | Homo sapiens | CHEMBL807597 | cell-based format |
| CHEMBL119413 |  |
IC50 | = | 1.7 | nM | 391.88 | CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1Cl | Homo sapiens | CHEMBL807597 | cell-based format |
| CHEMBL432067 |  |
IC50 | = | 1.8 | nM | 357.43 | CCCCCCCCc1ccc(CCC(N)COP(=O)(O)O)cc1 | Homo sapiens | CHEMBL807599 | cell-based format |
| CHEMBL323617 |  |
IC50 | = | 1.8 | nM | 395.44 | CCCCCCCc1nc(-c2ccc(CNCCCP(=O)(O)O)cc2)no1 | Homo sapiens | CHEMBL807597 | cell-based format |
| CHEMBL331054 |  |
IC50 | = | 1.8 | nM | 371.46 | CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1C | Homo sapiens | CHEMBL807597 | cell-based format |
| CHEMBL118815 |  |
IC50 | = | 1.9 | nM | 508.43 | CCCCCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC | Homo sapiens | CHEMBL807597 | cell-based format |
| CHEMBL119873 |  |
IC50 | = | 2.0 | nM | 375.42 | CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1F | Homo sapiens | CHEMBL807597 | cell-based format |
| CHEMBL5192525 |  |
IC50 | = | 2.6 | nM | 538.94 | COc1cc(OC)c(NC(=O)Cn2c(=O)n(CC(=O)Nc3ccc(O)cc3)c(=O)c3ccccc32)cc1Cl | Homo sapiens | CHEMBL5108826 | single protein format |
| CHEMBL116981 |  |
IC50 | = | 2.6 | nM | 389.48 | CCCCCCc1ccc(-c2ccc(CNCCCP(=O)(O)O)cc2)cc1 | Homo sapiens | CHEMBL807597 | cell-based format |
| CHEMBL119354 |  |
IC50 | = | 2.9 | nM | 436.33 | CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1Br | Homo sapiens | CHEMBL807597 | cell-based format |
| CHEMBL332667 |  |
IC50 | = | 3.0 | nM | 515.22 | CCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1Br | Homo sapiens | CHEMBL807597 | cell-based format |
| CHEMBL3401386 |  |
IC50 | = | 3.0 | nM | 563.67 | CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(=O)NC)cc3)c2)CC1 | Homo sapiens | CHEMBL3405604 | cell-based format |
| CHEMBL3401383 |  |
IC50 | = | 3.7 | nM | 549.64 | CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(N)=O)cc3)c2)CC1 | Homo sapiens | CHEMBL3405604 | cell-based format |
| CHEMBL117910 |  |
IC50 | = | 3.9 | nM | 480.38 | CCCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC | Homo sapiens | CHEMBL807598 | cell-based format |