O75912 | DGKI_HUMAN | Diacylglycerol kinase iota (DGKI)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00130 | C1_1 | 251–309 | |
| PF00609 | DAGK_acc | 526–683 | |
| PF00781 | DAGK_cat | 376–485 | |
| PF12796 | Ank_2 | 925–1017 | |
| PF23578 | DGKI | 711–860 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5424446 |  |
IC50 | = | 3.0 | nM | 516.51 | Cn1c(=O)c([N+](=O)[O-])c(N2CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)c2nc(C#N)ccc21 | Homo sapiens | CHEMBL5363633 | single protein format |
| CHEMBL5413938 |  |
IC50 | = | 1000.0 | nM | 491.5 | Cn1c(=O)c([N+](=O)[O-])c(N2CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)c2ncccc21 | Homo sapiens | CHEMBL5363633 | single protein format |