O75493 | CAH11_HUMAN | Carbonic anhydrase-related protein 11 (CA11)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00194 | Carb_anhydrase - Eukaryotic-type carbonic anhydrase | 57~300 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4080604 |  |
Ki | = | 1.2 | nM | 477.48 | NS(=O)(=O)c1ccc(NC(=S)N/N=C2\C(=O)Nc3ccc(S(=O)(=O)[O-])cc32)cc1.[Na+] | Homo sapiens | CHEMBL4036367 | assay format |
| CHEMBL4097126 |  |
Ki | = | 4.1 | nM | 420.43 | NS(=O)(=O)c1ccc(NC(=S)N/N=C2\C(=O)Nc3ccc([N+](=O)[O-])cc32)cc1 | Homo sapiens | CHEMBL4036367 | assay format |
| CHEMBL4081547 |  |
Ki | = | 4.5 | nM | 393.43 | NS(=O)(=O)c1ccc(NC(=S)N/N=C2\C(=O)Nc3ccc(F)cc32)cc1 | Homo sapiens | CHEMBL4036367 | assay format |
| CHEMBL4070963 |  |
Ki | = | 5.7 | nM | 389.46 | Cc1ccc2c(c1)/C(=N/NC(=S)Nc1ccc(S(N)(=O)=O)cc1)C(=O)N2 | Homo sapiens | CHEMBL4036367 | assay format |
| CHEMBL20 |  |
Ki | = | 5.7 | nM | 222.25 | CC(=O)Nc1nnc(S(N)(=O)=O)s1 | Homo sapiens | CHEMBL4036367 | assay format |
| CHEMBL4061260 |  |
Ki | = | 5.8 | nM | 409.88 | NS(=O)(=O)c1ccc(NC(=S)N/N=C2\C(=O)Nc3ccc(Cl)cc32)cc1 | Homo sapiens | CHEMBL4036367 | assay format |
| CHEMBL4069928 |  |
Ki | = | 5.9 | nM | 501.33 | NS(=O)(=O)c1ccc(NC(=S)N/N=C2\C(=O)Nc3ccc(I)cc32)cc1 | Homo sapiens | CHEMBL4036367 | assay format |
| CHEMBL4099555 |  |
Ki | = | 6.0 | nM | 459.43 | NS(=O)(=O)c1ccc(NC(=S)N/N=C2\C(=O)Nc3ccc(OC(F)(F)F)cc32)cc1 | Homo sapiens | CHEMBL4036367 | assay format |
| CHEMBL4089415 |  |
Ki | = | 6.1 | nM | 454.33 | NS(=O)(=O)c1ccc(NC(=S)N/N=C2\C(=O)Nc3ccc(Br)cc32)cc1 | Homo sapiens | CHEMBL4036367 | assay format |
| CHEMBL4064015 |  |
Ki | = | 6.3 | nM | 533.23 | NS(=O)(=O)c1ccc(NC(=S)N/N=C2\C(=O)Nc3c(Br)cc(Br)cc32)cc1 | Homo sapiens | CHEMBL4036367 | assay format |
| CHEMBL4091812 |  |
Ki | = | 6.9 | nM | 375.44 | NS(=O)(=O)c1ccc(NC(=S)N/N=C2\C(=O)Nc3ccccc32)cc1 | Homo sapiens | CHEMBL4036367 | assay format |
| CHEMBL4104834 |  |
Ki | = | 45.5 | nM | 393.43 | NS(=O)(=O)c1ccc(NC(=S)N/N=C2\C(=O)Nc3c(F)cccc32)cc1 | Homo sapiens | CHEMBL4036367 | assay format |
| CHEMBL4093328 |  |
Ki | = | 82.3 | nM | 444.33 | NS(=O)(=O)c1ccc(NC(=S)N/N=C2\C(=O)Nc3c(Cl)cc(Cl)cc32)cc1 | Homo sapiens | CHEMBL4036367 | assay format |
| CHEMBL4072614 |  |
Ki | = | 87.3 | nM | 409.88 | NS(=O)(=O)c1ccc(NC(=S)N/N=C2\C(=O)Nc3c(Cl)cccc32)cc1 | Homo sapiens | CHEMBL4036367 | assay format |