O75475 | PSIP1_HUMAN | PC4 and SFRS1-interacting protein (PSIP1)

Pfam Domain Table

AccessionDomainRangeColor
PF00855PWWP - PWWP domain8~87
PF11467LEDGF - Lens epithelium-derived growth factor (LEDGF)349~449

3D structures mapped by conservation among orthologs

[ Domain: "SH3" // PWWP ]

 PyMOL session

[ Domain: "Conserved domain common to transcription factors TFIIS, elongin A, CRSP70" // LEDGF ]

 PyMOL session


[ Alpha Fold Model ] (go)



Known binders annotated in ChEMBL

 IC50 CSV
Only the first 20 rows are shown.
molecule_chembl_idstructureassay_typerelation valueunitmol_wtsmilesorganism assay_chembl_idbao_label
CHEMBL3981070 IC50 = 470.0 nM 387.52 CCCC(C(=O)O)c1c(C)nc2cc3c(cc2c1-c1ccc(C)cc1)CCCC3 Homo sapiens CHEMBL3887244 single protein format
CHEMBL3966037 IC50 = 470.0 nM 387.52 CCCC(C(=O)O)c1c(C)nc2ccc3c(c2c1-c1ccc(C)cc1)CCCC3 Homo sapiens CHEMBL3887244 single protein format
CHEMBL3964350 IC50 = 550.0 nM 417.55 Cc1ccc(-c2c(C(OC(C)(C)C)C(=O)O)c(C)nc3cc4c(cc23)CCCC4)cc1 Homo sapiens CHEMBL3887245 single protein format