O75365 | TP4A3_HUMAN | Protein tyrosine phosphatase type IVA 3 (PTP4A3)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF22785 | Tc-R-P - Polymorphic toxin system, DSP-PTPase phosphatase | 34~123 |
3D structures mapped by conservation among orthologs
[ Domain: "(Phosphotyrosine protein) phosphatases II" // DSPc ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4471843 |  |
IC50 | = | 30.0 | nM | 257.27 | O=C1NC(=O)c2cc(-c3ccccc3)sc2C1=O | Homo sapiens | CHEMBL4434552 | assay format |
| CHEMBL4445621 |  |
IC50 | = | 35.0 | nM | 256.29 | N=C1C(=O)NC(=O)c2cc(-c3ccccc3)sc21 | Homo sapiens | CHEMBL4434552 | assay format |
| CHEMBL4862502 |  |
IC50 | = | 206.0 | nM | 562.69 | N=C1C(=O)NC(=O)c2cc(-c3ccc(OCC(=O)NCCCNC(=O)CC45CC6CC(CC(C6)C4)C5)cc3)sc21 | Homo sapiens | CHEMBL4823015 | single protein format |
| CHEMBL3393171 |  |
IC50 | = | 240.0 | nM | 242.3 | Nc1c[nH]c(=O)c2cc(-c3ccccc3)sc12 | Homo sapiens | CHEMBL3395080 | single protein format |
| CHEMBL55 |  |
IC50 | = | 300.0 | nM | 340.43 | N=C(N)c1ccc(OCCCCCOc2ccc(C(=N)N)cc2)cc1 | Homo sapiens | CHEMBL4434547 | single protein format |
| CHEMBL2397162 |  |
IC50 | = | 800.0 | nM | 383.49 | COc1ccccc1COc1ccccc1/C=C/C=C1\SC(=S)NC1=O | Homo sapiens | CHEMBL2400558 | single protein format |
| CHEMBL207428 |  |
IC50 | = | 900.0 | nM | 459.62 | O=C1NC(=S)S/C1=C\c1cc(-c2csc3ccccc23)ccc1OCc1ccccc1 | Homo sapiens | CHEMBL871238 | single protein format |
| CHEMBL207958 |  |
IC50 | = | 900.0 | nM | 485.22 | O=C1NC(=S)S/C1=C\c1cc(Br)ccc1OCc1ccccc1Br | Homo sapiens | CHEMBL871238 | single protein format |