O75351 | VPS4B_HUMAN | Vacuolar protein sorting-associated protein 4B (VPS4B)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00004 | AAA - ATPase family associated with various cellular activities (AAA) | 170~300 | |
| PF04212 | MIT - MIT (microtubule interacting and transport) domain | 8~74 | |
| PF09336 | Vps4_C - Vps4 C terminal oligomerisation domain | 381~441 | |
| PF17862 | AAA_lid_3 - AAA+ lid domain | 324~362 |
3D structures mapped by conservation among orthologs
[ Domain: "AAA+ ATPase lid domain" // Vps4_C_N ]
[ Domain: "MIT domain" // MIT ]
[ Domain: "P-loop containing nucleoside triphosphate hydrolases" // Sigma54_activat ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4572843 |  |
IC50 | = | 710.0 | nM | 462.56 | Fc1ccc(C(CCCNCC2CCc3[nH]c4ccc(F)cc4c3C2)c2ccc(F)cc2)cc1 | Homo sapiens | CHEMBL4356082 | single protein format |