O60930 | RNH1_HUMAN | Ribonuclease H1 (RNASEH1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00075 | RNase_H - RNase H | 140~281 | |
| PF01693 | Cauli_VI - Ribonuclease H1 N-terminal domain | 28~70 |
3D structures mapped by conservation among orthologs
[ Domain: "L9 N-domain-like" // Cauli_VI ]
[ Domain: "Ribonuclease H-like" // RNase_H ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL16755 |  |
IC50 | = | 120.0 | nM | 177.16 | O=C1Cc2ccccc2C(=O)N1O | Homo sapiens | CHEMBL1058996 | single protein format |
| CHEMBL562080 |  |
IC50 | = | 170.0 | nM | 415.65 | O=C(O)c1nc(Cc2c(Br)sc3ccc(Cl)cc23)nc(O)c1O | Homo sapiens | CHEMBL1058996 | single protein format |
| CHEMBL550937 |  |
IC50 | = | 600.0 | nM | 180.2 | CC(C)c1ccc(O)c(=O)c(O)c1 | Homo sapiens | CHEMBL1058996 | single protein format |
| CHEMBL572124 |  |
IC50 | = | 900.0 | nM | 355.14 | COc1ccc(Cc2nc(O)c(O)c(C(=O)O)n2)cc1Br | Homo sapiens | CHEMBL1058996 | single protein format |