O60906 | NSMA_HUMAN | Sphingomyelin phosphodiesterase 2 (SMPD2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF03372 | Exo_endo_phos - Endonuclease/Exonuclease/phosphatase family | 14~272 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5284450 |  |
IC50 | = | 300.0 | nM | 486.57 | COc1ccc(-c2c(C)cc3c(N4CC[C@@H](NC(=O)Oc5ccccc5)C4)cc(C)nn23)cc1OC | Homo sapiens | CHEMBL5226613 | single protein format |
| CHEMBL418376 |  |
IC50 | = | 1000.0 | nM | 485.67 | CC[C@@H](C)/C=C(\C)C[C@@H](C)C[C@@H](C)/C=C/C=C/C=C/C(=O)N[C@H](CO)C[C@@]1(O)C(=O)C=C[C@@H]2O[C@@H]21 | Homo sapiens | CHEMBL751441 | assay format |
| CHEMBL310981 |  |
IC50 | = | 1000.0 | nM | 519.61 | CCCCCCCCCCCCCCCC(=O)N[C@@H](CC(F)(F)P(=O)(O)O)[C@H](O)c1ccccc1 | Homo sapiens | CHEMBL872837 | assay format |
| CHEMBL5278618 |  |
IC50 | = | 1000.0 | nM | 408.5 | COc1ccc(-c2c(C)cc3c(N4CC[C@@H](NC(C)=O)C4)cc(C)nn23)cc1OC | Homo sapiens | CHEMBL5226613 | single protein format |