O60755 | GALR3_HUMAN | Galanin receptor type 3 (GALR3)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 34~291 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL209497 |  |
Ki | = | 5.0 | nM | 479.5 | O=C1/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc2N1c1cccc(OCCN2CCCC2)c1 | Homo sapiens | CHEMBL866716 | single protein format |
| CHEMBL209498 |  |
Ki | = | 8.0 | nM | 493.53 | O=C1/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc2N1c1cccc(OCCN2CCCCC2)c1 | Homo sapiens | CHEMBL866716 | single protein format |
| CHEMBL378991 |  |
Ki | = | 15.0 | nM | 511.54 | CCN(CC)CC(O)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 | Homo sapiens | CHEMBL866716 | single protein format |
| CHEMBL210288 |  |
Ki | = | 17.0 | nM | 366.34 | O=C1/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc2N1c1ccccc1 | Homo sapiens | CHEMBL864918 | single protein format |
| CHEMBL378825 |  |
Ki | = | 21.0 | nM | 495.55 | CCN(CC)CCCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 | Homo sapiens | CHEMBL866716 | single protein format |
| CHEMBL211398 |  |
Ki | = | 26.0 | nM | 453.46 | CN(C)CCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 | Homo sapiens | CHEMBL866716 | single protein format |
| CHEMBL209642 |  |
Ki | = | 27.0 | nM | 511.54 | CCN(CC)C[C@H](O)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 | Homo sapiens | CHEMBL866716 | single protein format |
| CHEMBL377468 |  |
Ki | = | 29.0 | nM | 467.49 | CN(C)CCCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 | Homo sapiens | CHEMBL866716 | single protein format |
| CHEMBL213893 |  |
Ki | = | 34.0 | nM | 495.55 | CCN(CC)CCCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 | Homo sapiens | CHEMBL866716 | single protein format |
| CHEMBL383941 |  |
Ki | = | 38.0 | nM | 467.49 | CCN(CC)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 | Homo sapiens | CHEMBL866716 | single protein format |
| CHEMBL209476 |  |
Ki | = | 45.0 | nM | 509.57 | CCN(CC)CCCCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 | Homo sapiens | CHEMBL866716 | single protein format |
| CHEMBL211031 |  |
Ki | = | 49.0 | nM | 493.53 | O=C1/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc2N1c1cccc(OCCCN2CCCC2)c1 | Homo sapiens | CHEMBL866716 | single protein format |
| CHEMBL211169 |  |
Ki | = | 52.0 | nM | 360.38 | CCC(CC)N1C(=O)/C(=N/c2ccc(C(F)(F)F)cc2)c2ccccc21 | Homo sapiens | CHEMBL864918 | single protein format |
| CHEMBL377328 |  |
Ki | = | 70.0 | nM | 509.57 | CCN(CC)CCCCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 | Homo sapiens | CHEMBL866716 | single protein format |
| CHEMBL211467 |  |
Ki | = | 78.0 | nM | 481.52 | CCN(CC)CCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 | Homo sapiens | CHEMBL866716 | single protein format |
| CHEMBL209481 |  |
Ki | = | 87.0 | nM | 481.52 | CCN(CC)CCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 | Homo sapiens | CHEMBL866716 | single protein format |
| CHEMBL387401 |  |
Ki | = | 89.0 | nM | 328.29 | C#CCN1C(=O)/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc21 | Homo sapiens | CHEMBL864918 | single protein format |
| CHEMBL209730 |  |
Ki | = | 89.0 | nM | 453.46 | CN(C)CCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1 | Homo sapiens | CHEMBL866716 | single protein format |
| CHEMBL212729 |  |
Ki | = | 150.0 | nM | 331.2 | C=CCN1C(=O)/C(=N/c2ccc(Cl)c(Cl)c2)c2ccccc21 | Homo sapiens | CHEMBL864918 | single protein format |
| CHEMBL211522 |  |
Ki | = | 290.0 | nM | 511.54 | CCN(CC)C[C@@H](O)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1 | Homo sapiens | CHEMBL866716 | single protein format |