O60733 | PLPL9_HUMAN | 85/88 kDa calcium-independent phospholipase A2 (PLA2G6)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00023 | Ank - Ankyrin repeat | 349~380 | |
| PF01734 | Patatin - Patatin-like phospholipase | 481~664 | |
| PF12796 | Ank_2 - Ankyrin repeats (3 copies) | 163~248 | |
| PF12796 | Ank_2 - Ankyrin repeats (3 copies) | 260~345 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4476476 |  |
IC50 | = | 1.0 | nM | 246.35 | CCC[C@H]1OC(=O)[C@@H]1CCCCc1ccccc1 | Homo sapiens | CHEMBL4401976 | single protein format |
| CHEMBL6223 |  |
IC50 | = | 30.0 | nM | 364.18 | O=C1O/C(=C/I)CCC1c1cccc2ccccc12 | Homo sapiens | CHEMBL760624 | tissue-based format |
| CHEMBL89506 |  |
IC50 | = | 63.0 | nM | 256.33 | CCCCCCCCSCC(=O)C(F)(F)F | Homo sapiens | CHEMBL4413446 | single protein format |
| CHEMBL269758 |  |
IC50 | = | 95.0 | nM | 262.31 | C#C/C=C1\CCC(c2cccc3ccccc23)C(=O)O1 | Homo sapiens | CHEMBL760624 | tissue-based format |
| CHEMBL6206 |  |
IC50 | = | 140.0 | nM | 317.18 | O=C1O/C(=C/Br)CCC1c1cccc2ccccc12 | Homo sapiens | CHEMBL760624 | tissue-based format |
| CHEMBL6228 |  |
IC50 | = | 190.0 | nM | 364.18 | O=C1O/C(=C\I)CCC1c1cccc2ccccc12 | Homo sapiens | CHEMBL760624 | tissue-based format |
| CHEMBL148674 |  |
IC50 | = | 590.0 | nM | 380.4 | CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccc2n1Cc1ccccc1 | Homo sapiens | CHEMBL4413446 | single protein format |