O60603 | TLR2_HUMAN | Toll-like receptor 2 (TLR2)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00560 | LRR_1 | 55–74 | |
| PF01463 | LRRCT | 561–585 | |
| PF01582 | TIR | 641–768 | |
| PF13855 | LRR_8 | 77–134 | |
| PF13855 | LRR_8 | 477–535 |
3D structures mapped by conservation among orthologs
[ Domain: "Leucine-rich repeats" // LRR_8_3 ]
[ Domain: "Leucine-rich repeats" // LRR_8_1 ]
[ Domain: "Toll/Interleukin receptor TIR domain" // TIR ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5186900 |  |
IC50 | = | 350.0 | nM | 226.24 | O=[N+]([O-])/C=C/c1cccc(-c2ccccn2)c1 | Homo sapiens | CHEMBL5108191 | cell-based format |
| CHEMBL5202822 |  |
IC50 | = | 520.0 | nM | 241.25 | O=[N+]([O-])/C=C/c1cccc(Nc2ccccn2)c1 | Homo sapiens | CHEMBL5108191 | cell-based format |