O60602 | TLR5_HUMAN | Toll-like receptor 5 (TLR5)

Pfam Domain Table

AccessionDomainRangeColor
PF00560LRR_1 - Leucine Rich Repeat549~570
PF01582TIR - TIR domain692~846
PF13855LRR_8 - Leucine rich repeat85~128
PF13855LRR_8 - Leucine rich repeat135~182
PF13855LRR_8 - Leucine rich repeat289~348
PF13855LRR_8 - Leucine rich repeat360~415
PF13855LRR_8 - Leucine rich repeat491~538

3D structures mapped by conservation among orthologs

[ Domain: "Leucine-rich repeats" // LRR_8_3 ]

 PyMOL session

[ Domain: "Leucine-rich repeats" // LRR_8 ]

 PyMOL session

[ Domain: "Toll/Interleukin receptor TIR domain" // TIR ]

 PyMOL session


[ Alpha Fold Model ] (go)



Known binders annotated in ChEMBL

 IC50 CSV
Only the first 20 rows are shown.
molecule_chembl_idstructureassay_typerelation valueunitmol_wtsmilesorganism assay_chembl_idbao_label
CHEMBL4795753 IC50 = 850.0 nM 453.56 c1ccc(Cn2c(Sc3ncnc4c3sc3ncccc34)nnc2-c2ccncc2)cc1 Homo sapiens CHEMBL4687757 cell-based format