O43897 | TLL1_HUMAN | Tolloid-like protein 1 (TLL1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00431 | CUB - CUB domain | 349~458 | |
| PF00431 | CUB - CUB domain | 462~571 | |
| PF00431 | CUB - CUB domain | 618~727 | |
| PF00431 | CUB - CUB domain | 774~883 | |
| PF00431 | CUB - CUB domain | 887~1000 | |
| PF01400 | Astacin - Astacin (Peptidase family M12A) | 157~347 | |
| PF14670 | FXa_inhibition - Coagulation Factor Xa inhibitory site | 582~614 | |
| PF14670 | FXa_inhibition - Coagulation Factor Xa inhibitory site | 734~769 |
3D structures mapped by conservation among orthologs
[ Domain: "Metalloproteases ("zincins") catalytic domain" // Astacin ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4207308 |  |
IC50 | = | 100.0 | nM | 429.52 | CCCCC[C@@H](C(=O)NCNC(=O)c1ccc(-c2ccccc2)o1)[C@@H](CC)N(O)C=O | Homo sapiens | CHEMBL4199881 | single protein format |
| CHEMBL4214046 |  |
Ki | = | 0.24 | nM | 553.55 | CCCCC[C@@H](C(=O)NCNC(=O)c1ccc(-c2cc(OCC)cc(P(=O)(O)O)c2)o1)[C@@H](CC)N(O)C=O | Homo sapiens | CHEMBL4199903 | single protein format |