O43895 | XPP2_HUMAN | Xaa-Pro aminopeptidase 2 (XPNPEP2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00557 | Peptidase_M24 - Metallopeptidase family M24 | 365~575 | |
| PF01321 | Creatinase_N - Creatinase/Prolidase N-terminal domain | 55~185 | |
| PF16188 | Peptidase_M24_C - C-terminal region of peptidase_M24 | 585~648 | |
| PF16189 | Creatinase_N_2 - Creatinase/Prolidase N-terminal domain | 195~361 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4110944 |  |
IC50 | = | 3.7 | nM | 457.57 | CC(C)C[C@H](S)C(=O)N1C[C@@H](F)C[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CC[C@@H](C(=O)O)C1 | Homo sapiens | CHEMBL3887729 | single protein format |
| CHEMBL3954917 |  |
IC50 | = | 3.9 | nM | 427.57 | CC(C)C[C@H](S)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N(C)[C@@H](C)C(=O)O | Homo sapiens | CHEMBL3887729 | single protein format |
| CHEMBL3932740 |  |
IC50 | = | 9.7 | nM | 439.58 | CC(C)C[C@H](S)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@@H]1C(=O)O | Homo sapiens | CHEMBL3887729 | single protein format |
| CHEMBL3960222 |  |
IC50 | = | 26.0 | nM | 439.58 | CC(C)C[C@H](S)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CC[C@H](C(=O)O)C1 | Homo sapiens | CHEMBL3887729 | single protein format |
| CHEMBL2369868 |  |
IC50 | = | 230.0 | nM | 328.41 | CC(C)C[C@@H](N)[C@H](O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O | Homo sapiens | CHEMBL644753 | assay format |
| CHEMBL2369858 |  |
IC50 | = | 430.0 | nM | 328.41 | CC(C)C[C@H](N)[C@@H](O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O | Homo sapiens | CHEMBL644753 | assay format |