O43868 | S28A2_HUMAN | Sodium/nucleoside cotransporter 2 (SLC28A2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01773 | Nucleos_tra2_N - Na+ dependent nucleoside transporter N-terminus | 178~250 | |
| PF07662 | Nucleos_tra2_C - Na+ dependent nucleoside transporter C-terminus | 362~583 | |
| PF07670 | Gate - Nucleoside recognition | 259~355 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3808747 |  |
IC50 | = | 62.0 | nM | 519.6 | OCCCCOc1cc(CNc2nc3ccccc3n2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)ccc1-c1ccccc1 | Homo sapiens | CHEMBL3813158 | cell-based format |
| CHEMBL3427690 |  |
IC50 | = | 640.0 | nM | 448.48 | Nc1ncnc2c1nc(NCc1ccc(-c3ccccc3)cc1)n2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O | Homo sapiens | CHEMBL3428943 | cell-based format |
| CHEMBL3809613 |  |
IC50 | = | 940.0 | nM | 536.59 | Nc1ncnc2c1nc(NCc1ccc(-c3ccccc3)c(OCCCCO)c1)n2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O | Homo sapiens | CHEMBL3813158 | cell-based format |
| CHEMBL3809974 |  |
IC50 | = | 1000.0 | nM | 449.47 | Nc1ncnc2c1nc(NCc1ccc(-c3cccnc3)cc1)n2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O | Homo sapiens | CHEMBL3813158 | cell-based format |