O43865 | SAHH2_HUMAN | S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00670 | AdoHcyase_NAD - S-adenosyl-L-homocysteine hydrolase, NAD binding domain | 289~449 | |
| PF05221 | AdoHcyase - S-adenosyl-L-homocysteine hydrolase | 104~239 |
3D structures mapped by conservation among orthologs
[ Domain: "NAD(P)-binding Rossmann-fold domains" // AdoHcyase_NAD ]
[ Domain: "Formate/glycerate dehydrogenase catalytic domain-like" // AdoHcyase ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2059155 |  |
IC50 | = | 2.7 | nM | 341.17 | Nc1ncc(Br)c2c1ncn2[C@@H]1C=C(CO)[C@@H](O)[C@H]1O | Homo sapiens | CHEMBL3757541 | single protein format |
| CHEMBL3753637 |  |
IC50 | = | 3.2 | nM | 262.27 | Nc1nccc2c1ncn2C1=C[C@H](CO)[C@@H](O)[C@H]1O | Homo sapiens | CHEMBL3757541 | single protein format |
| CHEMBL3753746 |  |
IC50 | = | 13.0 | nM | 341.17 | Nc1ncc(Br)c2c1ncn2C1=C[C@H](CO)[C@@H](O)[C@H]1O | Homo sapiens | CHEMBL3757541 | single protein format |