O43791 | SPOP_HUMAN | Speckle-type POZ protein (SPOP)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00651 | BTB | 192–296 | |
| PF22486 | MATH_2 | 33–161 | |
| PF24570 | BACK_BPM_SPOP | 301–351 |
3D structures mapped by conservation among orthologs
[ Domain: "TRAF domain-like" // MATH ]
[ Domain: "BACK domain" // BACK ]
[ Domain: "POZ domain" // BTB ]
[ Domain: "POZ domain" // BACK,BTB ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5432865 |  |
IC50 | = | 580.0 | nM | 368.8 | C=CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)c3ccc(CCl)o3)[C@H]2SC1 | Homo sapiens | CHEMBL5360394 | cell-based format |