O43603 | GALR2_HUMAN | Galanin receptor type 2 (GALR2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 42~292 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4128926 |  |
IC50 | = | 0.19 | nM | 583.78 | CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c2ccccc12 | Homo sapiens | CHEMBL4121479 | single protein format |
| CHEMBL1922007 |  |
IC50 | = | 330.0 | nM | 459.47 | COc1ccc(Nc2nc(Nc3ccc(OC(F)(F)F)cc3)cc(N3CCCCC3)n2)cc1 | Homo sapiens | CHEMBL1924415 | single protein format |
| CHEMBL1922006 |  |
IC50 | = | 380.0 | nM | 459.47 | COc1ccc(Nc2nc(Nc3cccc(OC(F)(F)F)c3)cc(N3CCCCC3)n2)cc1 | Homo sapiens | CHEMBL1924415 | single protein format |
| CHEMBL1922013 |  |
IC50 | = | 380.0 | nM | 407.49 | COc1ccc(Nc2nc(Nc3cccc(F)c3C)cc(N3CCCCC3)n2)cc1 | Homo sapiens | CHEMBL1924415 | single protein format |
| CHEMBL1922010 |  |
IC50 | = | 430.0 | nM | 423.49 | COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(N3CCCCC3)n2)cc1 | Homo sapiens | CHEMBL1924415 | single protein format |
| CHEMBL1922005 |  |
IC50 | = | 440.0 | nM | 403.53 | COc1ccc(Nc2nc(Nc3cc(C)ccc3C)cc(N3CCCCC3)n2)cc1 | Homo sapiens | CHEMBL1924415 | single protein format |
| CHEMBL1922009 |  |
IC50 | = | 540.0 | nM | 441.48 | COc1ccc(Nc2nc(Nc3cccc(OC(F)F)c3)cc(N3CCCCC3)n2)cc1 | Homo sapiens | CHEMBL1924415 | single protein format |
| CHEMBL1921999 |  |
IC50 | = | 550.0 | nM | 473.5 | COc1ccc(Nc2cc(Nc3cccc(OC(F)(F)F)c3)nc(NC3CCCCC3)n2)cc1 | Homo sapiens | CHEMBL1924415 | single protein format |
| CHEMBL1922003 |  |
IC50 | = | 560.0 | nM | 529.59 | Cc1c(F)cccc1Nc1cc(N2CCCCC2)nc(N2CCCN(c3ncccc3C(F)(F)F)CC2)n1 | Homo sapiens | CHEMBL1924415 | single protein format |
| CHEMBL1921996 |  |
IC50 | = | 770.0 | nM | 455.51 | COc1ccc(Nc2cc(Nc3cccc(OC(F)F)c3)nc(NC3CCCCC3)n2)cc1 | Homo sapiens | CHEMBL1924415 | single protein format |
| CHEMBL1922016 |  |
IC50 | = | 770.0 | nM | 437.52 | COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(N3CCCCCC3)n2)cc1 | Homo sapiens | CHEMBL1924415 | single protein format |
| CHEMBL1922008 |  |
IC50 | = | 780.0 | nM | 443.47 | COc1ccc(Nc2nc(Nc3ccc(C(F)(F)F)cc3)cc(N3CCCCC3)n2)cc1 | Homo sapiens | CHEMBL1924415 | single protein format |
| CHEMBL1921993 |  |
IC50 | = | 930.0 | nM | 391.48 | COc1ccc(Nc2cc(Nc3cccc(OC)c3)nc(N3CCCC3)n2)cc1 | Homo sapiens | CHEMBL1924415 | single protein format |
| CHEMBL1922012 |  |
IC50 | = | 980.0 | nM | 407.49 | COc1ccc(Nc2nc(Nc3ccc(F)cc3C)cc(N3CCCCC3)n2)cc1 | Homo sapiens | CHEMBL1924415 | single protein format |