O43174 | CP26A_HUMAN | Cytochrome P450 26A1 (CYP26A1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00067 | p450 - Cytochrome P450 | 45~472 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL1831083 |  |
IC50 | = | 0.35 | nM | 413.52 | CCOC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 | Homo sapiens | CHEMBL1833279 | single protein format |
| CHEMBL1831092 |  |
IC50 | = | 0.35 | nM | 400.48 | COC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1cncn1 | Homo sapiens | CHEMBL1833279 | single protein format |
| CHEMBL1766007 |  |
IC50 | = | 3.0 | nM | 415.49 | COC(=O)C(C)(C)C(c1ccc(Nc2ccc3cc(O)ccc3c2)cc1)n1ccnc1 | Homo sapiens | CHEMBL1768149 | microsome format |
| CHEMBL1766005 |  |
IC50 | = | 3.0 | nM | 399.49 | COC(=O)C(C)(C)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 | Homo sapiens | CHEMBL1768149 | microsome format |
| CHEMBL368448 |  |
IC50 | = | 3.3 | nM | 429.52 | CC(C(c1ccc2cc(OCc3ccc(C(=O)O)cc3)ccc2c1)n1ccnc1)N(C)C | Homo sapiens | CHEMBL832851 | single protein format |
| CHEMBL426789 |  |
IC50 | = | 3.5 | nM | 429.52 | CC(C(c1ccc2cc(OCc3cccc(C(=O)O)c3)ccc2c1)n1ccnc1)N(C)C | Homo sapiens | CHEMBL832851 | single protein format |
| CHEMBL224305 |  |
IC50 | = | 5.0 | nM | 377.52 | CCC(CC)[C@H](c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1 | Homo sapiens | CHEMBL996935 | cell-based format |
| CHEMBL459505 |  |
IC50 | = | 5.1 | nM | 377.52 | CCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1 | Homo sapiens | CHEMBL3789264 | cell-based format |
| CHEMBL2146987 |  |
IC50 | = | 5.7 | nM | 429.32 | COC(=O)C(C)(C)C(c1ccc(Nc2ccc(Br)nc2)cc1)n1ccnc1 | Homo sapiens | CHEMBL2148657 | microsome format |
| CHEMBL1766003 |  |
IC50 | = | 6.0 | nM | 399.49 | COC(=O)C(C)(C)C(c1ccc(Nc2cccc3ccccc23)cc1)n1ccnc1 | Homo sapiens | CHEMBL1768149 | microsome format |
| CHEMBL359627 |  |
IC50 | = | 6.0 | nM | 410.52 | CC(C(c1ccc2cc(OCc3ccc(C#N)cc3)ccc2c1)n1ccnc1)N(C)C | Homo sapiens | CHEMBL832851 | single protein format |
| CHEMBL2147090 |  |
IC50 | = | 6.7 | nM | 394.43 | COC(=O)C(C)(C)C(c1ccc(Nc2ccc3c(c2)OCO3)cc1)n1cncn1 | Homo sapiens | CHEMBL2148657 | microsome format |
| CHEMBL181309 |  |
IC50 | = | 7.0 | nM | 443.55 | COC(=O)c1cccc(COc2ccc3cc(C(C(C)N(C)C)n4ccnc4)ccc3c2)c1 | Homo sapiens | CHEMBL832851 | single protein format |
| CHEMBL1766001 |  |
IC50 | = | 8.0 | nM | 393.44 | COC(=O)C(C)(C)C(c1ccc(Nc2ccc3c(c2)OCO3)cc1)n1ccnc1 | Homo sapiens | CHEMBL1768149 | microsome format |
| CHEMBL1766006 |  |
IC50 | = | 8.0 | nM | 429.52 | COC(=O)C(C)(C)C(c1ccc(Nc2ccc3cc(OC)ccc3c2)cc1)n1ccnc1 | Homo sapiens | CHEMBL1768149 | microsome format |
| CHEMBL179550 |  |
IC50 | = | 8.0 | nM | 459.55 | CC(C(c1ccc2cc(OCc3ccc(OCC(=O)O)cc3)ccc2c1)n1ccnc1)N(C)C | Homo sapiens | CHEMBL832851 | single protein format |
| CHEMBL2146981 |  |
IC50 | = | 9.4 | nM | 417.43 | COC(=O)C(C)(C)C(c1ccc(Nc2ccc(C(F)(F)F)cc2)cc1)n1ccnc1 | Homo sapiens | CHEMBL2148657 | microsome format |
| CHEMBL3617993 |  |
IC50 | = | 10.0 | nM | 378.51 | CC(C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1)N(C)C | Homo sapiens | CHEMBL3620652 | single protein format |
| CHEMBL1766008 |  |
IC50 | = | 10.0 | nM | 390.44 | COC(=O)C(C)(C)C(c1ccc(Nc2nc3ccccc3o2)cc1)n1ccnc1 | Homo sapiens | CHEMBL1768149 | microsome format |
| CHEMBL1766000 |  |
IC50 | = | 10.0 | nM | 349.43 | COC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1ccnc1 | Homo sapiens | CHEMBL1768149 | microsome format |