O15527 | OGG1_HUMAN | N-glycosylase/DNA lyase (OGG1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00730 | HhH-GPD - HhH-GPD superfamily base excision DNA repair protein | 143~285 | |
| PF07934 | OGG_N - 8-oxoguanine DNA glycosylase, N-terminal domain | 26~141 |
3D structures mapped by conservation among orthologs
[ Domain: "DNA-glycosylase" // HhH-GPD ]
[ Domain: "TATA-box binding protein-like" // OGG_N ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4441163 |  |
IC50 | = | 220.0 | nM | 261.13 | NNC(=O)c1sc2cccc(Cl)c2c1Cl | Homo sapiens | CHEMBL4422181 | single protein format |
| CHEMBL4470975 |  |
IC50 | = | 270.0 | nM | 320.85 | CC1CCCC/C1=N/NC(=O)c1sc2ccccc2c1Cl | Homo sapiens | CHEMBL4422181 | single protein format |
| CHEMBL4436904 |  |
IC50 | = | 300.0 | nM | 226.69 | NNC(=O)c1sc2ccccc2c1Cl | Homo sapiens | CHEMBL4422180 | single protein format |
| CHEMBL4437745 |  |
IC50 | = | 330.0 | nM | 332.79 | O=C(N/N=C/c1ccc(F)cc1)c1sc2ccccc2c1Cl | Homo sapiens | CHEMBL4422181 | single protein format |
| CHEMBL4568814 |  |
IC50 | = | 340.0 | nM | 282.34 | O=C(NN=C1CCCCC1)c1cc2ccccc2cc1O | Homo sapiens | CHEMBL4422181 | single protein format |
| CHEMBL124433 |  |
IC50 | = | 390.0 | nM | 215.05 | NNC(=O)c1ccc(Br)cc1 | Homo sapiens | CHEMBL4422180 | single protein format |
| CHEMBL4564367 |  |
IC50 | = | 630.0 | nM | 295.18 | O=C(NN=C1CCCCC1)c1ccc(Br)cc1 | Homo sapiens | CHEMBL4422181 | single protein format |