O15455 | TLR3_HUMAN | Toll-like receptor 3 (TLR3)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01582 | TIR | 759–859 | |
| PF13516 | LRR_6 | 196–209 | |
| PF13855 | LRR_8 | 52–111 | |
| PF13855 | LRR_8 | 123–183 | |
| PF13855 | LRR_8 | 274–330 | |
| PF13855 | LRR_8 | 409–467 | |
| PF13855 | LRR_8 | 480–542 | |
| PF13855 | LRR_8 | 562–622 | |
| PF17968 | Tlr3_TMD | 698–730 |
3D structures mapped by conservation among orthologs
[ Domain: "Leucine-rich repeats" // LRR_8_3 ]
[ Domain: "Leucine-rich repeats" // LRR_8_1 ]
[ Domain: "Toll-like receptor 3 transmembrane domain" // EUF08789 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL19954 |  |
IC50 | = | 110.0 | nM | 276.34 | COc1ccc2[nH]c3c(C)c4ccncc4c(C)c3c2c1 | Homo sapiens | CHEMBL5337597 | cell-based format |